Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages

BACKGROUND: Macrophages play a dual role in neuroinflammatory disorders such as multiple sclerosis (MS). They are involved in lesion onset and progression but can also promote the resolution of inflammation and repair of damaged tissue. In this study, we investigate if and how phloretin, a flavonoid...

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Detalles Bibliográficos
Autores principales: Dierckx, Tess, Haidar, Mansour, Grajchen, Elien, Wouters, Elien, Vanherle, Sam, Loix, Melanie, Boeykens, Annick, Bylemans, Dany, Hardonnière, Kévin, Kerdine-Römer, Saadia, Bogie, Jeroen F. J., Hendriks, Jerome J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254976/
https://www.ncbi.nlm.nih.gov/pubmed/34218792
http://dx.doi.org/10.1186/s12974-021-02194-z

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