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Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study

BACKGROUND: Induced hypernatremia and hyperosmolarity is protective in animal models of lung injury. We hypothesized that increasing and maintaining plasma sodium between 145 and 150 mmol/l in patients with moderate-to-severe ARDS would be safe and will reduce lung injury. This was a prospective ran...

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Detalles Bibliográficos
Autores principales: Bihari, Shailesh, Prakash, Shivesh, Dixon, Dani L., Cavallaro, Elena, Bersten, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255097/
https://www.ncbi.nlm.nih.gov/pubmed/34219190
http://dx.doi.org/10.1186/s40635-021-00399-3