Cargando…

Luteolin inhibits H(2)O(2)-induced cellular senescence via modulation of SIRT1 and p53

Luteolin, a sort of flavonoid, has been reported to be involved in neuroprotective function via suppression of neuroinflammation. In this study, we investigated the protective effect of luteolin against oxidative stress-induced cellular senescence and its molecular mechanism using hydrogen peroxide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Ri Zhe, Li, Bing Si, Gao, Shang Shang, Seo, Jae Ho, Choi, Byung-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255127/ https://www.ncbi.nlm.nih.gov/pubmed/34187948 http://dx.doi.org/10.4196/kjpp.2021.25.4.297

Ejemplares similares

DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts
por: Li, Bing Si, et al.
Publicado: (2021)

Galangin Reverses H(2)O(2)-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling
por: Lee, Jian-Jr, et al.
Publicado: (2022)

Luteolin Prevents H(2)O(2)-Induced Apoptosis in H9C2 Cells through Modulating Akt-P53/Mdm2 Signaling Pathway
por: Chang, Hong, et al.
Publicado: (2016)

Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
por: Tran, Duc, et al.
Publicado: (2014)

Metoprolol Protects Against Arginine Vasopressin-Induced Cellular Senescence in H9C2 Cardiomyocytes by Regulating the Sirt1/p53/p21 Axis
por: Li, Qiang, et al.
Publicado: (2021)

Cocoa Polyphenol Extract Inhibits Cellular Senescence via Modulation of SIRT1 and SIRT3 in Auditory Cells
por: Rivas-Chacón, Luz del Mar, et al.
Publicado: (2023)

Luteolin suppresses TNF-α-induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF-κB pathway
por: Xie, Tian, et al.
Publicado: (2022)

Role of p53 in the Regulation of Cellular Senescence
por: Mijit, Mahmut, et al.
Publicado: (2020)

Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis
por: Lim, Chae Jin, et al.
Publicado: (2017)

Luteolin-7-O-β-d-Glucoside Inhibits Cellular Energy Production Interacting with HEK2 in Keratinocytes
por: Palombo, Ramona, et al.
Publicado: (2019)

Specificity of H(2)O(2) signaling in leaf senescence: is the ratio of H(2)O(2) contents in different cellular compartments sensed in Arabidopsis plants?
por: Zentgraf, Ulrike, et al.
Publicado: (2022)

TP53 and MTOR crosstalk to regulate cellular senescence
por: Galluzzi, Lorenzo, et al.
Publicado: (2010)

The Flavonoid Luteolin, but Not Luteolin-7-O-Glucoside, Prevents a Transthyretin Mediated Toxic Response
por: Iakovleva, Irina, et al.
Publicado: (2015)

SIRT1 confers protection against UVB- and H(2)O(2)-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes
por: Cao, Cong, et al.
Publicado: (2009)

Luteolin attenuates neuronal apoptosis in the hippocampi of diabetic encephalopathy rats☆
por: Ren, Guiru, et al.
Publicado: (2013)

SIRT3 consolidates heterochromatin and counteracts senescence
por: Diao, Zhiqing, et al.
Publicado: (2021)

The Kindlin2-p53-SerpinB2 signaling axis is required for cellular senescence in breast cancer
por: Sossey-Alaoui, Khalid, et al.
Publicado: (2019)

Tetrahydroxy stilbene glycoside attenuates endothelial cell premature senescence induced by H(2)O(2) through the microRNA-34a/SIRT1 pathway
por: Zhang, Lixuan, et al.
Publicado: (2022)

Sirt1: Def-eating senescence?
por: Fusco, Salvatore, et al.
Publicado: (2012)

Regulation of cellular senescence via the FOXO4‐p53 axis
por: Bourgeois, Benjamin, et al.
Publicado: (2018)

High-affinity Na(+)-dependent dicarboxylate cotransporter promotes cellular senescence by inhibiting SIRT1
por: Liu, Weiping, et al.
Publicado: (2010)

Correction to ‘SIRT3 consolidates heterochromatin and counteracts senescence’
por: Diao, Zhiqing, et al.
Publicado: (2021)

Luteolin regulates the distribution and function of organelles by controlling SIRT1 activity during postovulatory oocyte aging
por: Xing, Xupeng, et al.
Publicado: (2023)

Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats
por: Zhang, Kai-Kai, et al.
Publicado: (2021)

Luteolin Protects Chondrocytes from H(2)O(2)-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling
por: Zhou, Zhiqiang, et al.
Publicado: (2022)

Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation
por: Kilic Eren, Mehtap, et al.
Publicado: (2015)

Luteolin Prevents UVB-Induced Skin Photoaging Damage by Modulating SIRT3/ROS/MAPK Signaling: An in vitro and in vivo Studies
por: Mu, Jing, et al.
Publicado: (2021)

Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms
por: Luo, Yuanyuan, et al.
Publicado: (2017)

SIRT1 Is the Target Gene for 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence
por: Guo, Yan, et al.
Publicado: (2020)

Downregulation of JMJD2a and LSD1 is involved in CK2 inhibition-mediated cellular senescence through the p53-SUV39h1 pathway
por: Park, Jeong-Woo, et al.
Publicado: (2022)

Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity
por: Yang, Daqian, et al.
Publicado: (2016)

SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation
por: Zhao, Ganye, et al.
Publicado: (2016)

SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC
por: Lee, Namgyu, et al.
Publicado: (2016)

Apremilast prevents IL-17-induced cellular senescence in ATDC5 chondrocytes mediated by SIRT1
por: Wang, Benlong, et al.
Publicado: (2021)

Roflumilast Attenuates Doxorubicin-Induced Cardiotoxicity by Targeting Inflammation and Cellular Senescence in Cardiomyocytes Mediated by SIRT1
por: Zhang, Sheng, et al.
Publicado: (2021)

mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53
por: Jung, Seung Hee, et al.
Publicado: (2018)

Cellular senescence: ex vivo p53-dependent asymmetric cell kinetics
por: Rambhatla, Lakshmi, et al.
Publicado: (2001)

Centrosome Aberrations Associated with Cellular Senescence and p53 Localization at Supernumerary Centrosomes
por: Ohshima, Susumu
Publicado: (2012)

p53 Isoforms in Cellular Senescence- and Ageing-Associated Biological and Physiological Functions
por: Fujita, Kaori
Publicado: (2019)

FBXW7 inactivation induces cellular senescence via accumulation of p53
por: Gong, Longyuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7thjfqnejbijk12f8pjue800ak