Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management

Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is...

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Detalles Bibliográficos
Autores principales: Natesan, Vijayakumar, Kim, Sung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255138/
https://www.ncbi.nlm.nih.gov/pubmed/33888647
http://dx.doi.org/10.4062/biomolther.2020.204
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author Natesan, Vijayakumar
Kim, Sung-Jin
author_facet Natesan, Vijayakumar
Kim, Sung-Jin
author_sort Natesan, Vijayakumar
collection PubMed
description Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is intended to understand the nature of DN risk factors, progression, effects of glycemic levels, and stages of DN. We also explored the novel diagnostic and therapeutic approaches for DN such as gene therapy and stem cell treatments.
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spelling pubmed-82551382021-07-09 Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management Natesan, Vijayakumar Kim, Sung-Jin Biomol Ther (Seoul) Review Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is intended to understand the nature of DN risk factors, progression, effects of glycemic levels, and stages of DN. We also explored the novel diagnostic and therapeutic approaches for DN such as gene therapy and stem cell treatments. The Korean Society of Applied Pharmacology 2021-07-01 2021-04-23 /pmc/articles/PMC8255138/ /pubmed/33888647 http://dx.doi.org/10.4062/biomolther.2020.204 Text en Copyright © 2021, The Korean Society of Applied Pharmacology https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Natesan, Vijayakumar
Kim, Sung-Jin
Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
title Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
title_full Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
title_fullStr Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
title_full_unstemmed Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
title_short Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
title_sort diabetic nephropathy – a review of risk factors, progression, mechanism, and dietary management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255138/
https://www.ncbi.nlm.nih.gov/pubmed/33888647
http://dx.doi.org/10.4062/biomolther.2020.204
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