Computational modeling of microfluidic data provides high-throughput affinity estimates for monoclonal antibodies

Affinity measurement is a fundamental step in the discovery of monoclonal antibodies (mAbs) and of antigens suitable for vaccine development. Innovative affinity assays are needed due to the low throughput and/or limited dynamic range of available technologies. We combined microfluidic technology wi...

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Detalles Bibliográficos
Autores principales: Budroni, Sonia, Buricchi, Francesca, Cavallone, Andrea, Volpini, Gianfranco, Mariani, Alessandra, Lo Surdo, Paola, Blohmke, Christoph J., Del Giudice, Giuseppe, Medini, Duccio, Finco, Oretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Method Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255181/
https://www.ncbi.nlm.nih.gov/pubmed/34257845
http://dx.doi.org/10.1016/j.csbj.2021.06.024

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