Cargando…

Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer

PURPOSE: The impact of the interval between previous endoscopy and diagnosis on the treatment modality or mortality of undifferentiated (UD)-type gastric cancer is unclear. This study aimed to investigate the effect of endoscopic screening interval on the stage, cancer-related mortality, and treatme...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Ayoung, Chung, Hyunsoo, Lee, Hyuk-Joon, Cho, Soo-Jeong, Kim, Jue Lie, Ahn, Hye Seong, Suh, Yun-Suhk, Kong, Seong-Ho, Choe, Hwi Nyeong, Yang, Han-Kwang, Kim, Sang Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255304/
https://www.ncbi.nlm.nih.gov/pubmed/34234981
http://dx.doi.org/10.5230/jgc.2021.21.e19
_version_ 1783717878941351936
author Lee, Ayoung
Chung, Hyunsoo
Lee, Hyuk-Joon
Cho, Soo-Jeong
Kim, Jue Lie
Ahn, Hye Seong
Suh, Yun-Suhk
Kong, Seong-Ho
Choe, Hwi Nyeong
Yang, Han-Kwang
Kim, Sang Gyun
author_facet Lee, Ayoung
Chung, Hyunsoo
Lee, Hyuk-Joon
Cho, Soo-Jeong
Kim, Jue Lie
Ahn, Hye Seong
Suh, Yun-Suhk
Kong, Seong-Ho
Choe, Hwi Nyeong
Yang, Han-Kwang
Kim, Sang Gyun
author_sort Lee, Ayoung
collection PubMed
description PURPOSE: The impact of the interval between previous endoscopy and diagnosis on the treatment modality or mortality of undifferentiated (UD)-type gastric cancer is unclear. This study aimed to investigate the effect of endoscopic screening interval on the stage, cancer-related mortality, and treatment methods of UD-type gastric cancer. MATERIALS AND METHODS: We reviewed the medical records of newly diagnosed patients with UD gastric cancer in 2013, in whom the interval between previous endoscopy and diagnosis could be determined. The patients were classified into different groups according to the period from the previous endoscopy to diagnosis (<12 months, 12–23 months, 24–35 months, ≥36 months, and no history of endoscopy), and the outcomes were compared between the groups. In addition, patients who underwent endoscopic and surgical treatment were reclassified based on the final treatment results. RESULTS: The number of enrolled patients was 440, with males representing 64.1% of the study population; 11.8% of the participants reported that they had undergone endoscopy for the first time in their cancer diagnosis. The percentage of stage I cancer at diagnosis significantly decreased as the interval from the previous endoscopy to diagnosis increased (65.4%, 63.2%, 64.2%, 45.9%, and 35.2% for intervals of <12 months, 12–23 months, 24–35 months, ≥36 months, and no previous endoscopy, respectively, P<0.01). Cancer-related mortality was significantly lower for a 3-year interval of endoscopy (P<0.001). CONCLUSIONS: A 3-year interval of endoscopic screening reduces gastric-cancer-related mortality, particularly in cases of UD histology.
format Online
Article
Text
id pubmed-8255304
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Korean Gastric Cancer Association
record_format MEDLINE/PubMed
spelling pubmed-82553042021-07-06 Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer Lee, Ayoung Chung, Hyunsoo Lee, Hyuk-Joon Cho, Soo-Jeong Kim, Jue Lie Ahn, Hye Seong Suh, Yun-Suhk Kong, Seong-Ho Choe, Hwi Nyeong Yang, Han-Kwang Kim, Sang Gyun J Gastric Cancer Original Article PURPOSE: The impact of the interval between previous endoscopy and diagnosis on the treatment modality or mortality of undifferentiated (UD)-type gastric cancer is unclear. This study aimed to investigate the effect of endoscopic screening interval on the stage, cancer-related mortality, and treatment methods of UD-type gastric cancer. MATERIALS AND METHODS: We reviewed the medical records of newly diagnosed patients with UD gastric cancer in 2013, in whom the interval between previous endoscopy and diagnosis could be determined. The patients were classified into different groups according to the period from the previous endoscopy to diagnosis (<12 months, 12–23 months, 24–35 months, ≥36 months, and no history of endoscopy), and the outcomes were compared between the groups. In addition, patients who underwent endoscopic and surgical treatment were reclassified based on the final treatment results. RESULTS: The number of enrolled patients was 440, with males representing 64.1% of the study population; 11.8% of the participants reported that they had undergone endoscopy for the first time in their cancer diagnosis. The percentage of stage I cancer at diagnosis significantly decreased as the interval from the previous endoscopy to diagnosis increased (65.4%, 63.2%, 64.2%, 45.9%, and 35.2% for intervals of <12 months, 12–23 months, 24–35 months, ≥36 months, and no previous endoscopy, respectively, P<0.01). Cancer-related mortality was significantly lower for a 3-year interval of endoscopy (P<0.001). CONCLUSIONS: A 3-year interval of endoscopic screening reduces gastric-cancer-related mortality, particularly in cases of UD histology. The Korean Gastric Cancer Association 2021-06 2021-06-29 /pmc/articles/PMC8255304/ /pubmed/34234981 http://dx.doi.org/10.5230/jgc.2021.21.e19 Text en Copyright © 2021. Korean Gastric Cancer Association https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Ayoung
Chung, Hyunsoo
Lee, Hyuk-Joon
Cho, Soo-Jeong
Kim, Jue Lie
Ahn, Hye Seong
Suh, Yun-Suhk
Kong, Seong-Ho
Choe, Hwi Nyeong
Yang, Han-Kwang
Kim, Sang Gyun
Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer
title Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer
title_full Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer
title_fullStr Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer
title_full_unstemmed Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer
title_short Impact of the Interval between Previous Endoscopic Exam and Diagnosis on the Mortality and Treatment Modality of Undifferentiated-Type Gastric Cancer
title_sort impact of the interval between previous endoscopic exam and diagnosis on the mortality and treatment modality of undifferentiated-type gastric cancer
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255304/
https://www.ncbi.nlm.nih.gov/pubmed/34234981
http://dx.doi.org/10.5230/jgc.2021.21.e19
work_keys_str_mv AT leeayoung impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT chunghyunsoo impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT leehyukjoon impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT chosoojeong impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT kimjuelie impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT ahnhyeseong impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT suhyunsuhk impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT kongseongho impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT choehwinyeong impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT yanghankwang impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer
AT kimsanggyun impactoftheintervalbetweenpreviousendoscopicexamanddiagnosisonthemortalityandtreatmentmodalityofundifferentiatedtypegastriccancer