NQO1 Binds and Supports SIRT1 Function

Silent information regulator 2-related enzyme 1 (SIRT1) is an NAD(+)-dependent class III deacetylase and a key component of the cellular metabolic sensing pathway. The requirement of NAD(+) for SIRT1 activity led us to assume that NQO1, an NADH oxidoreductase producing NAD(+), regulates SIRT1 activi...

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Detalles Bibliográficos
Autores principales: Tsvetkov, Peter, Adler, Julia, Strobelt, Romano, Adamovich, Yaarit, Asher, Gad, Reuven, Nina, Shaul, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255383/
https://www.ncbi.nlm.nih.gov/pubmed/34234670
http://dx.doi.org/10.3389/fphar.2021.671929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255383/
https://www.ncbi.nlm.nih.gov/pubmed/34234670
http://dx.doi.org/10.3389/fphar.2021.671929

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