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NQO1 Binds and Supports SIRT1 Function
Silent information regulator 2-related enzyme 1 (SIRT1) is an NAD(+)-dependent class III deacetylase and a key component of the cellular metabolic sensing pathway. The requirement of NAD(+) for SIRT1 activity led us to assume that NQO1, an NADH oxidoreductase producing NAD(+), regulates SIRT1 activi...
Autores principales: | Tsvetkov, Peter, Adler, Julia, Strobelt, Romano, Adamovich, Yaarit, Asher, Gad, Reuven, Nina, Shaul, Yosef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255383/ https://www.ncbi.nlm.nih.gov/pubmed/34234670 http://dx.doi.org/10.3389/fphar.2021.671929 |
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