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OMRT-14. Small molecule circadian clock compounds exhibit potential as a novel therapy paradigm for glioblastoma

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumor type, claiming the lives of patients within 2 years of diagnosis. The major challenges in treating GBM are largely due to the biological characteristics of the tumor and the brain and pharmacokinetics of many drug...

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Detalles Bibliográficos
Autores principales: Chan, Priscilla, Hirota, Tsuyoshi, Qu, Meng, Zhang, Guoxin, Shah, Khalid, Wakimoto, Hiroaki, Kamenecka, Theodore, Solt, Laura, Rich, Jeremy, Kay, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255417/
http://dx.doi.org/10.1093/noajnl/vdab070.038

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