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OTEH-12. Assessing Adaptive Responses to Loss of Extrachromosomal DNA Amplification

BACKGROUND: Oncogene activation through somatic gene amplification happens frequently in GBM, with over 70% of these tumors presenting amplification of at least one putative driver gene, oftentimes in small extrachromosomal circular DNA segments composed of chromatin (ecDNA). A molecularly diverse a...

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Detalles Bibliográficos
Autores principales:	Berezovsky, Artem, Datta, Indrani, She, Ruicong, Hasselbach, Laura, Poisson, Laila, deCarvalho, Ana C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Supplement Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255421/ http://dx.doi.org/10.1093/noajnl/vdab070.051

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