OTME-17. Single cell characterization of the immune microenvironment of melanoma brain and leptomeningeal metastases

Melanoma brain metastases (MBM) and leptomeningeal metastases (LMM) are two manifestations of melanoma dissemination to the CNS with vastly different survival outcomes. Analysis of single cell RNA-Seq data from 43 clinical specimens has uncovered a distinct, immune-suppressed T cell landscape in the...

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Detalles Bibliográficos
Autores principales: Smalley, Inna, Chen, Zhihua, Phadke, Manali, Li, Jiannong, Yu, Xiaoqing, Wyatt, Clayton, Evernden, Brittany, Messina, Jane, Sarnaik, Amod, Sondak, Vernon, Zhang, Chaomei, Law, Vincent, Tran, Nam, Etame, Arnold, Macaulay, Robert, Eroglu, Zeynep, Forsyth, Peter, Rodriguez, Paulo, Chen, Ann, Smalley, Keiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255427/
http://dx.doi.org/10.1093/noajnl/vdab070.068

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