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OTME-15. Physical Confinement Induces Diverse Transcriptomic Changes and Chemoresistance in Migrating Glioblastoma Cells

Glioblastoma multiforme (GBM) cells migrating in physically confined environments are affected by mechanical stress that potentially lead to transcriptomic changes. To simulate those stresses, microfluidic channels were made with micro-patterned polydimethylsiloxane (PDMS) replicating the physical m...

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Detalles Bibliográficos
Autores principales: Battiste, James, Babu, Anish, Sharp, Rachel, Scott, Sydney, Dunn, Ian, Glenn, Chad, Kim, Young-tae, Jones, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255428/
http://dx.doi.org/10.1093/noajnl/vdab070.066

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