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OTME-15. Physical Confinement Induces Diverse Transcriptomic Changes and Chemoresistance in Migrating Glioblastoma Cells
Glioblastoma multiforme (GBM) cells migrating in physically confined environments are affected by mechanical stress that potentially lead to transcriptomic changes. To simulate those stresses, microfluidic channels were made with micro-patterned polydimethylsiloxane (PDMS) replicating the physical m...
Autores principales: | Battiste, James, Babu, Anish, Sharp, Rachel, Scott, Sydney, Dunn, Ian, Glenn, Chad, Kim, Young-tae, Jones, Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255428/ http://dx.doi.org/10.1093/noajnl/vdab070.066 |
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