Cargando…

OMRT-1. Cannabidiol converts NFKB into a tumor-suppressor in glioblastoma with defined antioxidative properties

BACKGROUND: The transcription factor NFKB drives neoplastic progression of many cancers including primary brain tumors (glioblastoma; GBM). Precise therapeutic modulation of NFKB-activity can suppress central oncogenic signalling pathways in GBM, but clinically applicable compounds to achieve this g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Volmar, Marie, Cheng, Jiying, Synowitz, Michael, Schick, Joel, Kälin, Roland, Glass, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Supplement Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255461/ http://dx.doi.org/10.1093/noajnl/vdab070.027

Ejemplares similares

Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties
por: Volmar, Marie N M, et al.
Publicado: (2021)

OMRT-11. The effect of microenvironment on glioblastoma stem cells therapeutic resistance
por: Turnsek, Tamara Lah, et al.
Publicado: (2021)

OMRT-12. Nanoparticle-based CRISPR-Cas9 delivery for anti-glioblastoma immunotherapy
por: Aguilar, Rocio, et al.
Publicado: (2021)

OMRT-14. Small molecule circadian clock compounds exhibit potential as a novel therapy paradigm for glioblastoma
por: Chan, Priscilla, et al.
Publicado: (2021)

OMRT-13. Delivery of Ubidecarenone (BPM 31510) to mitochondria effectuates metabolic reprogramming and redox activated apoptosis in Glioblastoma
por: Sarangarajan, Rangaprasad, et al.
Publicado: (2021)

OMRT-8. Precision targeting of cellular pathways with complementary diagnostics
por: Siddaway, Robert, et al.
Publicado: (2021)

OMRT-2. Liquid biopsy for patient stratification and monitoring of dacomitinib clinical trial in patients with EGFR amplified recurrent glioblastoma
por: Yekula, Anudeep, et al.
Publicado: (2021)

OMRT-6. Optimizing MDM2 inhibition for the treatment of high-grade glioma
por: Rendo, Veronica, et al.
Publicado: (2021)

OMRT-5. Therapy-induced reprogramming drives glioma vascular transdifferentiation and recurrence
por: Muthukrishnan, Sree Deepthi, et al.
Publicado: (2021)

OMRT-7. Angiogenesis inhibitors strongly synergize with therapeutics targeting tumor metabolism
por: Khadka, Sunada
Publicado: (2021)

OMRT-15. Multidisciplinary management of non-small cell lung cancer patients with leptomeningeal metastasis in the TKI era
por: Chen, Kuan-Yu, et al.
Publicado: (2021)

OMRT-3. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment
por: Varn, Frederick, et al.
Publicado: (2021)

OMRT-9. Effect of Pre-Operative Stereotactic Radiosurgery on Brain Metastasis: Analysis of DNA and RNA Genomic Profiles from Phase-II Clinical Trial NCT03398694
por: Shireman, Jack, et al.
Publicado: (2021)

APLN/APLNR Signaling Controls Key Pathological Parameters of Glioblastoma
por: Kälin, Roland E., et al.
Publicado: (2021)

OTME-1. TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression
por: Kälin, Roland, et al.
Publicado: (2021)

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor
por: Voce, David J., et al.
Publicado: (2014)

Glioblastoma Exhibits Inter-Individual Heterogeneity of TSPO and LAT1 Expression in Neoplastic and Parenchymal Cells
por: Cai, Linzhi, et al.
Publicado: (2020)

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility
por: Wirasinha, Rushika C., et al.
Publicado: (2020)

Updates on the Treatment of Essential Hypertension: A Summary of AHRQ’s Comparative Effectiveness Review of Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and Direct Renin Inhibitors
por: Powers, Benjamin, et al.
Publicado: (2011)

Cannabidiol Does Not Convert to Δ(9)-Tetrahydrocannabinol in an In Vivo Animal Model
por: Wray, Louise, et al.
Publicado: (2017)

Summary of AHRQ's Comparative Effectiveness Review of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Added to Standard Medical Therapy for Treating Stable Ischemic Heart Disease
por: White, Michael, et al.
Publicado: (2011)

Comparing Tumor Cell Invasion and Myeloid Cell Composition in Compatible Primary and Relapsing Glioblastoma
por: Zhao, Dongxu, et al.
Publicado: (2021)

Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets
por: Bayik, Defne, et al.
Publicado: (2022)

Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinase-dependent activation of NFkB
por: Demchenko, Yulia N., et al.
Publicado: (2014)

NFKB1 and Cancer: Friend or Foe?
por: Concetti, Julia, et al.
Publicado: (2018)

NFkB Pathway and Hodgkin Lymphoma
por: Jardin, Fabrice
Publicado: (2022)

Defining molecular glues with a dual-nanobody cannabidiol sensor
por: Cao, Shiyun, et al.
Publicado: (2022)

CLRM-03 INCIDENCE OF INTRACRANIAL HEMORRHAGE IN GLIOMA PATIENTS WITH VENOUS THROMBOEMBOLISM CONVERTED FROM LMWH TO APIXABAN
por: Aboud, Orwa, et al.
Publicado: (2022)

STMO-11 Supratotal resection of Glioblastoma with Methionine PET
por: Ko, Ozaki, et al.
Publicado: (2020)

DDRE-11. TARGETING FATTY ACID BIOSYNTHESIS IN GLIOBLASTOMA
por: Eyme, Katharina M, et al.
Publicado: (2021)

IM-8 Significance of IL-1 pathways in Glioblastoma
por: Kai, Keitaro, et al.
Publicado: (2021)

COT-12 Clinical feature of end-stage glioblastomas
por: Saito, Norihiko, et al.
Publicado: (2021)

OTEH-7. Molecular characterization of tumor stiffness in glioblastoma
por: Halldorsson, Skarphedinn, et al.
Publicado: (2021)

Cannabidiol in the Treatment of Epilepsy
por: von Wrede, Randi, et al.
Publicado: (2021)

Apelin Controls Angiogenesis-Dependent Glioblastoma Growth
por: Frisch, Anne, et al.
Publicado: (2020)

CBMS-09 Intercellular communication at glioblastoma stem cell niches
por: Hide, Takuichiro, et al.
Publicado: (2020)

SS-1 Therapeutic challenges for glioblastoma: Temozolomide and its issues?
por: Nagane, Motoo
Publicado: (2020)

DDRE-15. THE EVOLUTIONARY ENIGMA OF FATTY ACID DESATURATION IN GLIOBLASTOMA
por: Oatman, Nicole, et al.
Publicado: (2021)

DDRE-33. MELATONIN AS A MASTER METABOLIC SWITCH FOR GLIOBLASTOMA
por: Fernandez-Gil, Beatriz Irene, et al.
Publicado: (2021)

FSMP-02. CHANGES IN GLUTAMINE METABOLISM INDUCED BY OXALOACETATE IN GLIOBLASTOMA
por: Ijare, Omkar, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3dl59nmv8cp64gl764pa80vmok