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OTEH-8. Pathway-based approach reveals sensitivity to radiation when targeting E2F1 in Glioblastoma

The great phenotypic heterogeneity of glioblastoma (GBM) – both inter and intratumorally – has hindered therapeutic efforts. While genome-based molecular subtyping has revealed that GBMs may be parsed into several molecularly distinct categories, this insight has not translated to a significant exte...

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Detalles Bibliográficos
Autores principales: Alvarado, Alvaro, Tessema, Kaleab, Muthukrishnan, Sree, Kawaguchi, Riki, Swarup, Vivek, Goldman, Steven, Kornblum, Harley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255463/
http://dx.doi.org/10.1093/noajnl/vdab070.047