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Predicting human pharmacokinetics from preclinical data: clearance
We have streamlined known in vitro methods used to predict the clearance (CL) of small molecules in humans in this tutorial. There have been many publications on in vitro methods that are used at different steps of human CL prediction. The steps from initial intrinsic CL measurement in vitro to the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Clinical Pharmacology and Therapeutics
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255549/ https://www.ncbi.nlm.nih.gov/pubmed/34235120 http://dx.doi.org/10.12793/tcp.2021.29.e12 |