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Lipopolysaccharide-Activated Canine Platelets Upregulate High Mobility Group Box-1 via Toll-Like Receptor 4

High mobility group box-1 (HMGB1) and the toll-like receptor 4 (TLR4) axis is a key mediator of inflammation. Platelet-derived high mobility group box-1 (HMGB1) may also play a critical role in sepsis-mediated thrombosis resulting in complications like disseminated intravascular coagulation and mult...

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Detalles Bibliográficos
Autores principales: Li, Ronald H. L., Hommel, Caelin, Nguyen, Nghi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255672/
https://www.ncbi.nlm.nih.gov/pubmed/34235204
http://dx.doi.org/10.3389/fvets.2021.674678