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Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion

Salmonella spp. is one of the main foodborne pathogens around the world. It has a cyclic lifestyle that combines host colonization with survival outside the host, implying that Salmonella has to adapt to different conditions rapidly in order to survive. One of these environments outside the host is...

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Autores principales: Sholpan, Amanova, Lamas, Alexandre, Cepeda, Alberto, Franco, Carlos Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255907/
https://www.ncbi.nlm.nih.gov/pubmed/34250377
http://dx.doi.org/10.3934/microbiol.2021015
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author Sholpan, Amanova
Lamas, Alexandre
Cepeda, Alberto
Franco, Carlos Manuel
author_facet Sholpan, Amanova
Lamas, Alexandre
Cepeda, Alberto
Franco, Carlos Manuel
author_sort Sholpan, Amanova
collection PubMed
description Salmonella spp. is one of the main foodborne pathogens around the world. It has a cyclic lifestyle that combines host colonization with survival outside the host, implying that Salmonella has to adapt to different conditions rapidly in order to survive. One of these environments outside the host is the food production chain. In this environment, this foodborne pathogen has to adapt to different stress conditions such as acidic environments, nutrient limitation, desiccation, or biocides. One of the mechanisms used by Salmonella to survive under such conditions is biofilm formation. Quorum sensing plays an important role in the production of biofilms composed of cells from the same microorganism or from different species. It is also important in terms of food spoilage and regulates the pathogenicity and invasiveness of Salmonella by regulating Salmonella pathogenicity islands and flagella. Therefore, in this review, we will discuss the genetic mechanism involved in Salmonella quorum sensing, paying special attention to small RNAs and their post-regulatory activity in quorum sensing. We will further discuss the importance of this cell-to-cell communication mechanism in the persistence and spoilage of Salmonella in the food chain environment and the importance in the communication with microorganisms from different species. Subsequently, we will focus on the role of quorum sensing to regulate the virulence and invasion of host cells by Salmonella and on the interaction between Salmonella and other microbial species. This review offers an overview of the importance of quorum sensing in the Salmonella lifestyle.
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spelling pubmed-82559072021-07-09 Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion Sholpan, Amanova Lamas, Alexandre Cepeda, Alberto Franco, Carlos Manuel AIMS Microbiol Review Salmonella spp. is one of the main foodborne pathogens around the world. It has a cyclic lifestyle that combines host colonization with survival outside the host, implying that Salmonella has to adapt to different conditions rapidly in order to survive. One of these environments outside the host is the food production chain. In this environment, this foodborne pathogen has to adapt to different stress conditions such as acidic environments, nutrient limitation, desiccation, or biocides. One of the mechanisms used by Salmonella to survive under such conditions is biofilm formation. Quorum sensing plays an important role in the production of biofilms composed of cells from the same microorganism or from different species. It is also important in terms of food spoilage and regulates the pathogenicity and invasiveness of Salmonella by regulating Salmonella pathogenicity islands and flagella. Therefore, in this review, we will discuss the genetic mechanism involved in Salmonella quorum sensing, paying special attention to small RNAs and their post-regulatory activity in quorum sensing. We will further discuss the importance of this cell-to-cell communication mechanism in the persistence and spoilage of Salmonella in the food chain environment and the importance in the communication with microorganisms from different species. Subsequently, we will focus on the role of quorum sensing to regulate the virulence and invasion of host cells by Salmonella and on the interaction between Salmonella and other microbial species. This review offers an overview of the importance of quorum sensing in the Salmonella lifestyle. AIMS Press 2021-06-24 /pmc/articles/PMC8255907/ /pubmed/34250377 http://dx.doi.org/10.3934/microbiol.2021015 Text en © 2021 the Author(s), licensee AIMS Press https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) )
spellingShingle Review
Sholpan, Amanova
Lamas, Alexandre
Cepeda, Alberto
Franco, Carlos Manuel
Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
title Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
title_full Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
title_fullStr Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
title_full_unstemmed Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
title_short Salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
title_sort salmonella spp. quorum sensing: an overview from environmental persistence to host cell invasion
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255907/
https://www.ncbi.nlm.nih.gov/pubmed/34250377
http://dx.doi.org/10.3934/microbiol.2021015
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