The Heteromeric Complex Formed by Dopamine Receptor D(5) and CCR9 Leads the Gut Homing of CD4(+) T Cells Upon Inflammation

BACKGROUND AND AIMS: CD4(+) T cells constitute central players in inflammatory bowel diseases (IBDs), driving inflammation in the gut mucosa. Current evidence indicates that CCR9 and the integrin α4β7 are necessary and sufficient to imprint colonic homing on CD4(+) T cells upon inflammation. Interes...

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Detalles Bibliográficos
Autores principales: Osorio-Barrios, Francisco, Navarro, Gemma, Campos, Javier, Ugalde, Valentina, Prado, Carolina, Raïch, Iu, Contreras, Francisco, López, Ernesto, Espinoza, Alexandra, Lladser, Alvaro, Franco, Rafael, Pacheco, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255938/
https://www.ncbi.nlm.nih.gov/pubmed/33864900
http://dx.doi.org/10.1016/j.jcmgh.2021.04.006

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