Cargando…
Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans
BACKGROUND AND AIMS: A histopathological hallmark of chronic hepatitis B virus (HBV) infection is the presence of ground glass hepatocytes (GGHs). GGHs are liver cells that exhibit eosinophilic, granular, glassy cytoplasm in light microscopy and are characterized by accumulation of HBV surface (HBs)...
Autores principales: | Churin, Yuri, Irungbam, Karuna, Imiela, Christoph S., Schwarz, David, Mollenkopf, Hans-Joachim, Drebber, Uta, Odenthal, Margarete, Pak, Oleg, Huber, Magdalena, Glebe, Dieter, Roderfeld, Martin, Roeb, Elke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255940/ https://www.ncbi.nlm.nih.gov/pubmed/33766783 http://dx.doi.org/10.1016/j.jcmgh.2021.03.009 |
Ejemplares similares
-
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2
por: Irungbam, Karuna, et al.
Publicado: (2019) -
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice
por: Irungbam, Karuna, et al.
Publicado: (2020) -
Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4(-/-) Mice
por: Helmrich, Nora, et al.
Publicado: (2021) -
Schistosoma mansoni Egg–Secreted Antigens Activate Hepatocellular Carcinoma–Associated Transcription Factors c‐Jun and STAT3 in Hamster and Human Hepatocytes
por: Roderfeld, Martin, et al.
Publicado: (2019) -
Genomic Methylation Inhibits Expression of Hepatitis B Virus Envelope Protein in Transgenic Mice: A Non-Infectious Mouse Model to Study Silencing of HBV Surface Antigen Genes
por: Graumann, Franziska, et al.
Publicado: (2015)