Cargando…

Additive Antiproliferative and Antiangiogenic Effects of Metformin and Pemetrexed in a Non-Small-Cell Lung Cancer Xenograft Model

Lung cancer is heterogeneous and challenging to cope with once it has progressed. Chemotherapy is the first step once no active driver mutation has been discovered. Non-antitumor drugs have been found to be beneficial when used as adjuvants to chemotherapy. In this study, the additive effect and mec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jiun-Long, Lan, Ying-Wei, Tsai, Yi-Ting, Chen, Ying-Cheng, Staniczek, Theresa, Tsou, Yung-An, Yen, Chih-Ching, Chen, Chuan-Mu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255984/ https://www.ncbi.nlm.nih.gov/pubmed/34235153 http://dx.doi.org/10.3389/fcell.2021.688062

Ejemplares similares

Benefits of Metformin Combined with Pemetrexed-Based Platinum Doublets as a First-Line Therapy for Advanced Lung Adenocarcinoma Patients with Diabetes
por: Wang, Jiun-Long, et al.
Publicado: (2021)

Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis
por: Tsou, Yung-An, et al.
Publicado: (2021)

Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model
por: Chen, Ying-Cheng, et al.
Publicado: (2022)

The apatinib and pemetrexed combination has antitumor and antiangiogenic effects against NSCLC
por: Zhou, Ling, et al.
Publicado: (2023)

Antiproliferative and Antiangiogenic Activities of Smenospongine, a Marine Sponge Sesquiterpene Aminoquinone
por: Kong, Dexin, et al.
Publicado: (2011)

A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound
por: Ghițu, Alexandra, et al.
Publicado: (2019)

The effect of metformin use on hypopharyngeal squamous cell carcinoma in diabetes mellitus patients
por: Tsou, Yung-An, et al.
Publicado: (2019)

Lack of Efficacy of Combined Antiangiogenic Therapies in Xenografted Human Melanoma
por: Adamcic, Una, et al.
Publicado: (2012)

Evaluation of antiangiogenic and antiproliferative potential of the organic extract of green algae chlorella pyrenoidosa
por: Kyadari, Mahender, et al.
Publicado: (2013)

Antiangiogenic and antiproliferative effects of black pomegranate peel extract on melanoma cell line
por: Dana, N., et al.
Publicado: (2015)

Antiproliferative and Antiangiogenic Effects of Punica granatum Juice (PGJ) in Multiple Myeloma (MM)
por: Tibullo, Daniele, et al.
Publicado: (2016)

Antitumor and Antiangiogenic Activities of Curcumin in Cervical Cancer Xenografts in Nude Mice
por: Yoysungnoen-Chintana, Pornphrom, et al.
Publicado: (2014)

Therapeutic Effects of Kefir Peptides on Hemophilia-Induced Osteoporosis in Mice With Deficient Coagulation Factor VIII
por: Yen, Chih-Ching, et al.
Publicado: (2022)

Novel compounds with antiangiogenic and antiproliferative potency for growth control of testicular germ cell tumours
por: Nitzsche, B, et al.
Publicado: (2010)

Novel biogenic silver nanoconjugates of Abrus precatorius seed extracts and their antiproliferative and antiangiogenic efficacies
por: Kaur, Amritpal, et al.
Publicado: (2023)

Antiangiogenic effects of pazopanib in xenograft hepatocellular carcinoma models: evaluation by quantitative contrast-enhanced ultrasonography
por: Zhu, Xiao-Dong, et al.
Publicado: (2011)

Efficacy of combined icotinib and pemetrexed in EGFR mutant lung adenocarcinoma cell line xenografts
por: Cui, Jiadong, et al.
Publicado: (2018)

Antiproliferative, Antiangiogenic, and Antimigrastatic Effects of Oroxylum indicum (L.) Kurz Extract on Breast Cancer Cell
por: Chiraatthakit, Benjamas, et al.
Publicado: (2023)

Antiproliferative and Antiangiogenic Properties of New VEGFR-2-targeting 2-thioxobenzo[g]quinazoline Derivatives (In Vitro)
por: Abuelizz, Hatem A., et al.
Publicado: (2020)

Author Correction: Novel biogenic silver nanoconjugates of Abrus precatorius seed extracts and their antiproliferative and antiangiogenic efficacies
por: Kaur, Amritpal, et al.
Publicado: (2023)

Antiangiogenic therapy in breast cancer
por: Gampenrieder, Simon Peter, et al.
Publicado: (2017)

Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation
por: Lai, Hong-Yue, et al.
Publicado: (2021)

Benefits of Zebrafish Xenograft Models in Cancer Research
por: Chen, Xingyu, et al.
Publicado: (2021)

Kefir peptides attenuate atherosclerotic vascular calcification and osteoporosis in atherogenic diet-fed ApoE (−/−) knockout mice
por: Chang, Gary Ro-Lin, et al.
Publicado: (2023)

The antiproliferative potential and mechanism of action of metformin in MCF-7 cells
por: Bekezhankyzy, Zhibek, et al.
Publicado: (2023)

Effects of different combined regimens of cisplatin, metformin, and quercetin on nasopharyngeal carcinoma cells and subcutaneous xenografts
por: Chen, Zhongwei, et al.
Publicado: (2021)

Comparative evaluation of antiproliferative, antiangiogenic and apoptosis inducing potential of black tea polyphenols in the hamster buccal pouch carcinogenesis model
por: Letchoumy, Paramasivame Vidjaya, et al.
Publicado: (2007)

Metformin synergistic pemetrexed suppresses non‐small‐cell lung cancer cell proliferation and invasion in vitro
por: Zhang, Yan, et al.
Publicado: (2017)

MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway
por: Luo, Mao, et al.
Publicado: (2017)

The combination of cantharidin and antiangiogenic therapeutics presents additive antitumor effects against pancreatic cancer
por: Xu, Meng-Dan, et al.
Publicado: (2018)

Growth Hormone Improves Growth Retardation Induced by Rapamycin without Blocking Its Antiproliferative and Antiangiogenic Effects on Rat Growth Plate
por: Álvarez-García, Óscar, et al.
Publicado: (2012)

An In Vitro-In Vivo Evaluation of the Antiproliferative and Antiangiogenic Effect of Flavone Apigenin against SK-MEL-24 Human Melanoma Cell Line
por: Ghiƫu, Alexandra, et al.
Publicado: (2021)

Impact of pemetrexed chemotherapy on the gut microbiota and intestinal inflammation of patient-lung-derived tumor xenograft (PDX) mouse models
por: Pensec, Cindy, et al.
Publicado: (2020)

Early detection of antiangiogenic treatment responses in a mouse xenograft tumor model using quantitative perfusion MRI
por: Rajendran, Reshmi, et al.
Publicado: (2014)

Antiproliferative and apoptotic effects of telmisartan in human glioma cells
por: Chang, Yung-Lung, et al.
Publicado: (2023)

Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-β1 Signaling Pathways
por: Yi, Hao, et al.
Publicado: (2021)

Pemetrexed Induces S-Phase Arrest and Apoptosis via a Deregulated Activation of Akt Signaling Pathway
por: Chen, Kun-Chieh, et al.
Publicado: (2014)

Pemetrexed induced pneumonitis
por: Dhakal, Binod, et al.
Publicado: (2011)

Antiangiogenic therapy
por: Avitabile, T
Publicado: (2010)

Indirect comparison of efficacy and safety between immune checkpoint inhibitors and antiangiogenic therapy in advanced non–small-cell lung cancer
por: Chen, Jin-Hua, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5hu9s6pphrqbi1rj1qop48l44s