Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma

Immune cells infiltrating tumors are capable of significantly impacting carcinogenesis through cancer promotion and anticancer responses. There are many aspects of hepatocellular carcinoma (HCC) related T lymphocytes that are undergoing extensive studies, whereas the effect exerted by B lymphocytes...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Miaomiao, Wang, Danping, Fang, Yijiao, Zheng, Zhiying, Liu, Xinyang, Wu, Fan, Wang, Liangliang, Li, Xiao, Hui, Bingqing, Ma, Shijie, Tang, Weiwei, Pan, Xiongxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256159/
https://www.ncbi.nlm.nih.gov/pubmed/34235074
http://dx.doi.org/10.3389/fonc.2021.647854
_version_ 1783718043884453888
author Qin, Miaomiao
Wang, Danping
Fang, Yijiao
Zheng, Zhiying
Liu, Xinyang
Wu, Fan
Wang, Liangliang
Li, Xiao
Hui, Bingqing
Ma, Shijie
Tang, Weiwei
Pan, Xiongxiong
author_facet Qin, Miaomiao
Wang, Danping
Fang, Yijiao
Zheng, Zhiying
Liu, Xinyang
Wu, Fan
Wang, Liangliang
Li, Xiao
Hui, Bingqing
Ma, Shijie
Tang, Weiwei
Pan, Xiongxiong
author_sort Qin, Miaomiao
collection PubMed
description Immune cells infiltrating tumors are capable of significantly impacting carcinogenesis through cancer promotion and anticancer responses. There are many aspects of hepatocellular carcinoma (HCC) related T lymphocytes that are undergoing extensive studies, whereas the effect exerted by B lymphocytes remains a less researched area. In this study, the latest research on the effect of B lymphocytes as they infiltrate tumors in relation to HCC is presented. Their prognosis-related importance is analyzed, along with their function in the tumor microenvironment (TME), as well as the way that B cell biology can be employed to help create a B cell therapy strategy for HCC.
format Online
Article
Text
id pubmed-8256159
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-82561592021-07-06 Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma Qin, Miaomiao Wang, Danping Fang, Yijiao Zheng, Zhiying Liu, Xinyang Wu, Fan Wang, Liangliang Li, Xiao Hui, Bingqing Ma, Shijie Tang, Weiwei Pan, Xiongxiong Front Oncol Oncology Immune cells infiltrating tumors are capable of significantly impacting carcinogenesis through cancer promotion and anticancer responses. There are many aspects of hepatocellular carcinoma (HCC) related T lymphocytes that are undergoing extensive studies, whereas the effect exerted by B lymphocytes remains a less researched area. In this study, the latest research on the effect of B lymphocytes as they infiltrate tumors in relation to HCC is presented. Their prognosis-related importance is analyzed, along with their function in the tumor microenvironment (TME), as well as the way that B cell biology can be employed to help create a B cell therapy strategy for HCC. Frontiers Media S.A. 2021-06-21 /pmc/articles/PMC8256159/ /pubmed/34235074 http://dx.doi.org/10.3389/fonc.2021.647854 Text en Copyright © 2021 Qin, Wang, Fang, Zheng, Liu, Wu, Wang, Li, Hui, Ma, Tang and Pan https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Qin, Miaomiao
Wang, Danping
Fang, Yijiao
Zheng, Zhiying
Liu, Xinyang
Wu, Fan
Wang, Liangliang
Li, Xiao
Hui, Bingqing
Ma, Shijie
Tang, Weiwei
Pan, Xiongxiong
Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
title Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
title_full Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
title_fullStr Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
title_full_unstemmed Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
title_short Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
title_sort current perspectives on b lymphocytes in the immunobiology of hepatocellular carcinoma
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256159/
https://www.ncbi.nlm.nih.gov/pubmed/34235074
http://dx.doi.org/10.3389/fonc.2021.647854
work_keys_str_mv AT qinmiaomiao currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT wangdanping currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT fangyijiao currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT zhengzhiying currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT liuxinyang currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT wufan currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT wangliangliang currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT lixiao currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT huibingqing currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT mashijie currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT tangweiwei currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma
AT panxiongxiong currentperspectivesonblymphocytesintheimmunobiologyofhepatocellularcarcinoma

Ejemplares similares