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A re-examination of the SPYRAL HTN-OFF MED Pivotal trial with respect to the underlying model assumptions
BACKGROUND: The SPYRAL HTN-OFF MED Pivotal trial demonstrated that RDN was efficacious compared to a sham control. The underlying model was an extension of the analysis of covariance (ANCOVA) model, adjusted for baseline blood pressure (BP), and allowed borrowing of information from the previously r...
Autores principales: | Böhm, Michael, Fahy, Martin, Hickey, Graeme L., Pocock, Stuart, Brar, Sandeep, DeBruin, Vanessa, Weber, Michael A., Mahfoud, Felix, Kandzari, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256182/ https://www.ncbi.nlm.nih.gov/pubmed/34258470 http://dx.doi.org/10.1016/j.conctc.2021.100818 |
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