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HLA-dependent heterogeneity and macrophage immunoproteasome activation during lung COVID-19 disease
BACKGROUND: The worldwide pandemic caused by the SARS-CoV-2 virus is characterized by significant and unpredictable heterogeneity in symptoms that remains poorly understood. METHODS: Transcriptome and single cell transcriptome of COVID19 lung were integrated with deeplearning analysis of MHC class I...
Autores principales: | Desterke, Christophe, Turhan, Ali G., Bennaceur-Griscelli, Annelise, Griscelli, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256232/ https://www.ncbi.nlm.nih.gov/pubmed/34225749 http://dx.doi.org/10.1186/s12967-021-02965-5 |
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