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NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer

BACKGROUND: Trastuzumab (Herceptin) is the key systemic therapy for HER2-positive breast cancer. However, the initial response rate is limited to approximately 50% in patients. Moreover, most patients, especially at an advanced stage, eventually develop acquired resistance. Understanding the mechani...

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Detalles Bibliográficos
Autores principales:	Yuan, Yuan, Gao, Huanyao, Zhuang, Yongxian, Wei, Lixuan, Yu, Jia, Zhang, Zhe, Zhang, Lili, Wang, Liewei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256255/ https://www.ncbi.nlm.nih.gov/pubmed/34276814 http://dx.doi.org/10.1177/17588359211027836

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