Cargando…

Nintedanib attenuates peritoneal fibrosis by inhibiting mesothelial‐to‐mesenchymal transition, inflammation and angiogenesis

Nintedanib, an Food and Drug Administration (FDA) approved multiple tyrosine kinase inhibitor, exhibits an anti‐fibrotic effect in lung and kidneys. Its effect on peritoneal fibrosis remains unexplored. In this study, we found that nintedanib administration lessened chlorhexidine gluconate (CG)‐indu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Feng, Yu, Chao, Qin, Huan, Zhang, Shenglei, Fang, Lu, Wang, Yi, Wang, Jun, Cui, Binbin, Hu, Susie, Liu, Na, Zhuang, Shougang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256343/ https://www.ncbi.nlm.nih.gov/pubmed/33949772 http://dx.doi.org/10.1111/jcmm.16518

Ejemplares similares

Delayed Administration of Nintedanib Ameliorates Fibrosis Progression in CG-Induced Peritoneal Fibrosis Mouse Model
por: Cui, Binbin, et al.
Publicado: (2022)

Histone deacetylase 6 inhibition counteracts the epithelial–mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis
por: Xu, Liuqing, et al.
Publicado: (2017)

Targeting Src attenuates peritoneal fibrosis and inhibits the epithelial to mesenchymal transition
por: Wang, Jun, et al.
Publicado: (2017)

Trehalose ameliorates peritoneal fibrosis by promoting Snail degradation and inhibiting mesothelial-to-mesenchymal transition in mesothelial cells
por: Miyake, Taito, et al.
Publicado: (2020)

Requirement of Histone Deacetylase 6 for Interleukin-6 Induced Epithelial-Mesenchymal Transition, Proliferation, and Migration of Peritoneal Mesothelial Cells
por: Shi, Yingfeng, et al.
Publicado: (2021)

Shorter daily dwelling time in peritoneal dialysis attenuates the epithelial-to-mesenchymal transition of mesothelial cells
por: Lee, Yi-Che, et al.
Publicado: (2014)

Delayed administration of suramin attenuates peritoneal fibrosis in rats
por: Xiong, Chongxiang, et al.
Publicado: (2019)

Fibrin-Induced Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells as a Mechanism of Peritoneal Fibrosis: Effects of Pentoxifylline
por: Fang, Cheng-Chung, et al.
Publicado: (2012)

The Effect of Statin on Epithelial-Mesenchymal Transition in Peritoneal Mesothelial Cells
por: Chang, Tae Ik, et al.
Publicado: (2014)

Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
por: Kang, Seok Hui, et al.
Publicado: (2019)

Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer
por: Pascual-Antón, Lucía, et al.
Publicado: (2021)

Mechanisms of Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells During Peritoneal Dialysis
por: Lee, Hi Bahl, et al.
Publicado: (2007)

Matrine suppresses lipopolysaccharide-induced fibrosis in human peritoneal mesothelial cells by inhibiting the epithelial-mesenchymal transition
por: Li, Yi-Zheng, et al.
Publicado: (2019)

Tamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis
por: Loureiro, Jesús, et al.
Publicado: (2013)

Effect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells
por: Yu, Mina, et al.
Publicado: (2015)

Hydrogen sulfide inhibits epithelial-mesenchymal transition in peritoneal mesothelial cells
por: Cheng, Shengnan, et al.
Publicado: (2018)

RhoA/Rho-kinase triggers epithelial-mesenchymal transition in mesothelial cells and contributes to the pathogenesis of dialysis-related peritoneal fibrosis
por: Wang, Qinglian, et al.
Publicado: (2018)

Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis
por: Xie, Shunyun, et al.
Publicado: (2022)

miRNA589 Regulates Epithelial-Mesenchymal Transition in Human Peritoneal Mesothelial Cells
por: Zhang, Ke, et al.
Publicado: (2012)

MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial–mesenchymal transition (MMT) of human peritoneal mesothelial cells
por: Kimura, Yuki, et al.
Publicado: (2022)

Are the Mesothelial-to-Mesenchymal Transition, Sclerotic Peritonitis Syndromes, and Encapsulating Peritoneal Sclerosis Part of the Same Process?
por: Loureiro, Jesús, et al.
Publicado: (2013)

Blocking Posttranslational Core Fucosylation Ameliorates Rat Peritoneal Mesothelial Cell Epithelial-Mesenchymal Transition
por: Li, Long-Kai, et al.
Publicado: (2017)

Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells
por: Wang, Jinou, et al.
Publicado: (2018)

Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients
por: Ruiz-Carpio, Vicente, et al.
Publicado: (2017)

Mesothelial‐to‐mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer
por: Rynne‐Vidal, Angela, et al.
Publicado: (2017)

Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress
por: Shin, Hyun-Soo, et al.
Publicado: (2017)

Biological Effects of XyloCore, a Glucose Sparing PD Solution, on Mesothelial Cells: Focus on Mesothelial-Mesenchymal Transition, Inflammation and Angiogenesis
por: Masola, Valentina, et al.
Publicado: (2021)

Expression of XBP1s in peritoneal mesothelial cells is critical for inflammation-induced peritoneal fibrosis
por: Liu, An, et al.
Publicado: (2019)

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis
por: Strippoli, Raffaele, et al.
Publicado: (2020)

Vitamin D Can Ameliorate Chlorhexidine Gluconate-Induced Peritoneal Fibrosis and Functional Deterioration through the Inhibition of Epithelial-to-Mesenchymal Transition of Mesothelial Cells
por: Lee, Yi-Che, et al.
Publicado: (2015)

Activation of General Control Nonderepressible-2 Kinase Ameliorates Glucotoxicity in Human Peritoneal Mesothelial Cells, Preserves Their Integrity, and Prevents Mesothelial to Mesenchymal Transition
por: Eleftheriadis, Theodoros, et al.
Publicado: (2019)

AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4
por: Xiao, Li, et al.
Publicado: (2015)

Mechanisms of Peritoneal Mesothelial Cells in Peritoneal Adhesion
por: Wang, Ruipeng, et al.
Publicado: (2022)

MiR-30b is involved in methylglyoxal-induced epithelial-mesenchymal transition of peritoneal mesothelial cells in rats
por: Liu, Hong, et al.
Publicado: (2014)

New Insights Into the Role and Mechanism of Partial Epithelial-Mesenchymal Transition in Kidney Fibrosis
por: Sheng, Lili, et al.
Publicado: (2020)

Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization
por: Zhou, Xun, et al.
Publicado: (2023)

Inhibition of EZH2 mitigates peritoneal fibrosis and lipid precipitation in peritoneal mesothelial cells mediated by klotho
por: Wang, Qinglian, et al.
Publicado: (2023)

Elevated expression of HDAC6 in clinical peritoneal dialysis patients and its pathogenic role on peritoneal angiogenesis
por: Shi, Yingfeng, et al.
Publicado: (2020)

The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer
por: TSUKADA, TOMOYA, et al.
Publicado: (2012)

Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions
por: Wu, Zhung-Han, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_skkutk14klq6ispccspm84c7j2