Cargando…

A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer

BACKGROUND: tRNA-derived small noncoding RNAs (sncRNAs) are mainly categorized into tRNA halves (tiRNAs) and fragments (tRFs). Biological functions of tiRNAs in human solid tumor are attracting more and more attention, but researches concerning the mechanisms in tiRNAs-mediated tumorigenesis are rar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Litao, Lai, Hejing, Yang, Yichen, Hu, Jiaqian, Li, Zhe, Ma, Ben, Xu, Weibo, Liu, Wanlin, Wei, Wenjun, Li, Duanshu, Wang, Yu, Zhai, Qiwei, Ji, Qinghai, Liao, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256553/ https://www.ncbi.nlm.nih.gov/pubmed/34225773 http://dx.doi.org/10.1186/s13046-021-02024-3

Ejemplares similares

5’tiRNA-Pro-TGG, a novel tRNA halve, promotes oncogenesis in sessile serrated lesions and serrated pathway of colorectal cancer
por: Wang, Xin-Yuan, et al.
Publicado: (2023)

tRNA‐derived small RNA, 5'tiRNA‐Gly‐CCC, promotes skeletal muscle regeneration through the inflammatory response
por: Shen, Linyuan, et al.
Publicado: (2023)

Mechanisms of tRNA-derived fragments and tRNA halves in cancer treatment resistance
por: Zhang, Yue, et al.
Publicado: (2020)

Stress Response in Entamoeba histolytica Is Associated with Robust Processing of tRNA to tRNA Halves
por: Sharma, Manu, et al.
Publicado: (2023)

tiRNA Join Hematopoietic Niches
por: Tesio, Melania
Publicado: (2021)

5′ tRNA Halves: The Next Generation of Immune Signaling Molecules
por: Dhahbi, Joseph Mohsen
Publicado: (2015)

Staying together after the breakup: tRNA halves in extracellular fluids
por: Kaymak, Ebru, et al.
Publicado: (2023)

Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching
por: Rong, Zhihua, et al.
Publicado: (2023)

Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids
por: Costa, Bruno, et al.
Publicado: (2023)

A Novel tiRNA-Gly-GCC-1 Promotes Progression of Urothelial Bladder Carcinoma and Directly Targets TLR4
por: Qin, Chuan, et al.
Publicado: (2022)

Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment
por: Nechooshtan, Gal, et al.
Publicado: (2020)

tRFs and tRNA Halves: Novel Cellular Defenders in Multiple Biological Processes
por: Hou, Jiani, et al.
Publicado: (2022)

Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples
por: Van Goethem, Alan, et al.
Publicado: (2016)

Identification of aberrant tRNA-halves expression patterns in clear cell renal cell carcinoma
por: Nientiedt, Malin, et al.
Publicado: (2016)

5′-Terminal nucleotide variations in human cytoplasmic tRNA(HisGUG) and its 5′-halves
por: Shigematsu, Megumi, et al.
Publicado: (2017)

Blood, stress, and tiRNAs
por: Williams, Ruth
Publicado: (2009)

Antitumor Activities of tRNA-Derived Fragments and tRNA Halves from Non-pathogenic Escherichia coli Strains on Colorectal Cancer and Their Structure-Activity Relationship
por: Cao, Kai-Yue, et al.
Publicado: (2022)

Differential Expression and Bioinformatics Analysis of tRF/tiRNA in Endometriosis Patients
por: Li, Wang-shu, et al.
Publicado: (2022)

5′ tRNA halves are highly expressed in the primate hippocampus and might sequence-specifically regulate gene expression
por: Jehn, Julia, et al.
Publicado: (2020)

Analysis of tRNA halves (tsRNAs) in serum from cattle challenged with bovine viral diarrhea virus
por: Taxis, Tasia M., et al.
Publicado: (2019)

Elongation Factor Tu Prevents Misediting of Gly-tRNA(Gly) Caused by the Design Behind the Chiral Proofreading Site of D-Aminoacyl-tRNA Deacylase
por: Routh, Satya Brata, et al.
Publicado: (2016)

The Typical tRNA Co-Expresses Multiple 5′ tRNA Halves Whose Sequences and Abundances Depend on Isodecoder and Isoacceptor and Change with Tissue Type, Cell Type, and Disease
por: Akins, Robert Brian, et al.
Publicado: (2023)

A tRNA-mimic Strategy to Explore the Role of G34 of tRNA(Gly) in Translation and Codon Frameshifting
por: Janvier, Aurélie, et al.
Publicado: (2019)

YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression
por: Lyons, Shawn M., et al.
Publicado: (2016)

mt‐Ty 5'tiRNA regulates skeletal muscle cell proliferation and differentiation
por: Cao, Jun, et al.
Publicado: (2023)

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction
por: Dhahbi, Joseph M, et al.
Publicado: (2013)

Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity
por: Shen, Ning, et al.
Publicado: (2006)

Sequence Evidence in the Archaeal Genomes that tRNAs Emerged Through the Combination of Ancestral Genes as 5′ and 3′ tRNA Halves
por: Fujishima, Kosuke, et al.
Publicado: (2008)

Gene Expression Changes Induced by Trypanosoma cruzi Shed Microvesicles in Mammalian Host Cells: Relevance of tRNA-Derived Halves
por: Garcia-Silva, Maria R., et al.
Publicado: (2014)

Molecular envelope and atomic model of an anti-terminated glyQS T-box regulator in complex with tRNA(Gly)
por: Chetnani, Bhaskar, et al.
Publicado: (2017)

A specific tRNA half, 5’tiRNA-His-GTG, responds to hypoxia via the HIF1α/ANG axis and promotes colorectal cancer progression by regulating LATS2
por: Tao, En-Wei, et al.
Publicado: (2021)

Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5′ tRNA-Val-CAC-2-1 Half
por: Dhahbi, Joseph, et al.
Publicado: (2019)

eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function
por: Lyons, Shawn M, et al.
Publicado: (2020)

Integrated single-cell and bulk RNA sequencing analyses reveal a prognostic signature of cancer-associated fibroblasts in head and neck squamous cell carcinoma
por: Yang, Yichen, et al.
Publicado: (2022)

The Mitochondrial tRNA(Gly) T10003C Mutation May Not Be Associated with Diabetes Mellitus
por: Yuan, Q, et al.
Publicado: (2018)

A glyS T-box riboswitch with species-specific structural features responding to both proteinogenic and nonproteinogenic tRNA(Gly) isoacceptors
por: Apostolidi, Maria, et al.
Publicado: (2015)

SAT-109 tiRNA-5 Reflects the Severity of Mitochondrial Oxidative Stress in Nonalcoholic Fatty Liver Disease
por: Yang, Yashuang, et al.
Publicado: (2019)

Expression of tiRNA and tRF in APP/PS1 transgenic mice and the change of related proteins expression
por: Lu, Honglin, et al.
Publicado: (2021)

tRNA(GlyGCC)-Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression
por: Panoutsopoulou, Konstantina, et al.
Publicado: (2021)

Modulation of Escherichia coli Translation by the Specific Inactivation of tRNA(Gly) Under Oxidative Stress
por: Leiva, Lorenzo Eugenio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sf4mhen284lussuan5fotki5t0