Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease

INTRODUCTION: Asymptomatic and mildly symptomatic dominantly inherited Alzheimer's disease mutation carriers (DIAD‐MC) are ideal candidates for preventative treatment trials aimed at delaying or preventing dementia onset. Brain atrophy is an early feature of DIAD‐MC and could help predict risk...

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Detalles Bibliográficos
Autores principales: Keret, Ophir, Staffaroni, Adam M., Ringman, John M., Cobigo, Yann, Goh, Sheng‐Yang M., Wolf, Amy, Allen, Isabel Elaine, Salloway, Stephen, Chhatwal, Jasmeer, Brickman, Adam M., Reyes‐Dumeyer, Dolly, Bateman, Randal J., Benzinger, Tammie L.S., Morris, John C., Ances, Beau M., Joseph‐Mathurin, Nelly, Perrin, Richard J., Gordon, Brian A., Levin, Johannes, Vöglein, Jonathan, Jucker, Mathias, la Fougère, Christian, Martins, Ralph N., Sohrabi, Hamid R., Taddei, Kevin, Villemagne, Victor L., Schofield, Peter R., Brooks, William S., Fulham, Michael, Masters, Colin L., Ghetti, Bernardino, Saykin, Andrew J., Jack, Clifford R., Graff‐Radford, Neill R., Weiner, Michael, Cash, David M., Allegri, Ricardo F., Chrem, Patricio, Yi, Su, Miller, Bruce L., Rabinovici, Gil D., Rosen, Howard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Neuroimaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256623/
https://www.ncbi.nlm.nih.gov/pubmed/34258377
http://dx.doi.org/10.1002/dad2.12197

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