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Pomegranate peel extract polyphenols attenuate the SARS-CoV-2 S-glycoprotein binding ability to ACE2 Receptor: In silico and in vitro studies

The novel coronavirus disease (Covid-19) has become a major health threat globally. The interaction of SARS-CoV-2 spike (S) glycoprotein receptor-binding domain (RBD) with ACE2 receptor on host cells was recognized as the first step of virus infection and therefore as one of the primary targets for...

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Detalles Bibliográficos
Autores principales: Suručić, Relja, Travar, Maja, Petković, Miroslav, Tubić, Biljana, Stojiljković, Miloš P., Grabež, Milkica, Šavikin, Katarina, Zdunić, Gordana, Škrbić, Ranko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256661/
https://www.ncbi.nlm.nih.gov/pubmed/34246969
http://dx.doi.org/10.1016/j.bioorg.2021.105145