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Avascular necrosis as a part of ‘long COVID-19’
‘Long COVID-19’ can affect different body systems. At present, avascular necrosis (AVN) as a sequalae of ‘long COVID-19’ has yet not been documented. By large-scale use of life-saving corticosteroids in COVID-19 cases, we anticipate that there will be a resurgence of AVN cases. We report a series of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256728/ https://www.ncbi.nlm.nih.gov/pubmed/34215639 http://dx.doi.org/10.1136/bcr-2021-242101 |
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author | Agarwala, Sanjay R Vijayvargiya, Mayank Pandey, Prashant |
author_facet | Agarwala, Sanjay R Vijayvargiya, Mayank Pandey, Prashant |
author_sort | Agarwala, Sanjay R |
collection | PubMed |
description | ‘Long COVID-19’ can affect different body systems. At present, avascular necrosis (AVN) as a sequalae of ‘long COVID-19’ has yet not been documented. By large-scale use of life-saving corticosteroids in COVID-19 cases, we anticipate that there will be a resurgence of AVN cases. We report a series of three cases in which patients developed AVN of the femoral head after being treated for COVID-19 infection. The mean dose of prednisolone used in these cases was 758 mg (400–1250 mg), which is less than the mean cumulative dose of around 2000 mg steroid, documented in the literature as causative for AVN. Patients were symptomatic and developed early AVN presentation at a mean of 58 days after COVID-19 diagnosis as compared with the literature which shows that it generally takes 6 months to 1 year to develop AVN post steroid exposure. |
format | Online Article Text |
id | pubmed-8256728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-82567282021-07-23 Avascular necrosis as a part of ‘long COVID-19’ Agarwala, Sanjay R Vijayvargiya, Mayank Pandey, Prashant BMJ Case Rep Case Report ‘Long COVID-19’ can affect different body systems. At present, avascular necrosis (AVN) as a sequalae of ‘long COVID-19’ has yet not been documented. By large-scale use of life-saving corticosteroids in COVID-19 cases, we anticipate that there will be a resurgence of AVN cases. We report a series of three cases in which patients developed AVN of the femoral head after being treated for COVID-19 infection. The mean dose of prednisolone used in these cases was 758 mg (400–1250 mg), which is less than the mean cumulative dose of around 2000 mg steroid, documented in the literature as causative for AVN. Patients were symptomatic and developed early AVN presentation at a mean of 58 days after COVID-19 diagnosis as compared with the literature which shows that it generally takes 6 months to 1 year to develop AVN post steroid exposure. BMJ Publishing Group 2021-07-02 /pmc/articles/PMC8256728/ /pubmed/34215639 http://dx.doi.org/10.1136/bcr-2021-242101 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. |
spellingShingle | Case Report Agarwala, Sanjay R Vijayvargiya, Mayank Pandey, Prashant Avascular necrosis as a part of ‘long COVID-19’ |
title | Avascular necrosis as a part of ‘long COVID-19’ |
title_full | Avascular necrosis as a part of ‘long COVID-19’ |
title_fullStr | Avascular necrosis as a part of ‘long COVID-19’ |
title_full_unstemmed | Avascular necrosis as a part of ‘long COVID-19’ |
title_short | Avascular necrosis as a part of ‘long COVID-19’ |
title_sort | avascular necrosis as a part of ‘long covid-19’ |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256728/ https://www.ncbi.nlm.nih.gov/pubmed/34215639 http://dx.doi.org/10.1136/bcr-2021-242101 |
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