Cargando…

Lipophagy: A New Perspective of Natural Products in Type 2 Diabetes Mellitus Treatment

Autophagy has been reported to involve in the pathogenesis of type 2 diabetes mellitus (T2DM), which protects the insulin target tissues and pancreatic β-cells. However, autophagy is inhibited when the cells are lipid overload. That, in turn, increases the accumulation of fat. Lipotoxicity caused by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Mingyue, Yang, Xinyu, Wang, Zhenzhen, Long, Jianglan, Wang, Aiting, Zhang, Yi, Yan, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256822/ https://www.ncbi.nlm.nih.gov/pubmed/34234495 http://dx.doi.org/10.2147/DMSO.S310166

Ejemplares similares

Metabolite biomarkers of type 2 diabetes mellitus and pre-diabetes: a systematic review and meta-analysis
por: Long, Jianglan, et al.
Publicado: (2020)

Hypothalamic lipophagy and energetic balance
por: Singh, Rajat
Publicado: (2011)

A role for lipophagy in atherosclerosis
por: Laval, Thomas, et al.
Publicado: (2023)

Lipophagy: Connecting Autophagy and Lipid Metabolism
por: Singh, Rajat, et al.
Publicado: (2012)

Lipophagy and Alcohol-Induced Fatty Liver
por: Yang, Li, et al.
Publicado: (2019)

Lipolysis and lipophagy in lipid storage myopathies
por: Angelini, Corrado, et al.
Publicado: (2016)

Emerging Roles of Lipophagy in Health and Disease
por: Kounakis, Konstantinos, et al.
Publicado: (2019)

Emerging Roles of Lipophagy in Cancer Metastasis
por: Yin, Haimeng, et al.
Publicado: (2022)

Join the club: ORP8 is a lipophagy receptor
por: Wang, Zheng, et al.
Publicado: (2023)

The regulatory role of lipophagy in central nervous system diseases
por: Lan, Zhuo-qing, et al.
Publicado: (2023)

Hepatic lipophagy: New insights into autophagic catabolism of lipid droplets in the liver
por: Schulze, Ryan J., et al.
Publicado: (2017)

Active autophagy but not lipophagy in macrophages with defective lipolysis
por: Goeritzer, Madeleine, et al.
Publicado: (2015)

The Role of Macrophage Lipophagy in Reverse Cholesterol Transport
por: Jeong, Se-Jin, et al.
Publicado: (2017)

Lipophagy Impairment Is Associated With Disease Progression in NAFLD
por: Carotti, Simone, et al.
Publicado: (2020)

Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders
por: Shin, Dong Wook
Publicado: (2020)

The Expanding Role of Mitochondria, Autophagy and Lipophagy in Steroidogenesis
por: Bassi, Geetika, et al.
Publicado: (2021)

Alterations of Lipid Profile in Livers with Impaired Lipophagy
por: Jonas, Wenke, et al.
Publicado: (2022)

Defective Autophagy, Mitochondrial Clearance and Lipophagy in Niemann-Pick Type B Lymphocytes
por: Canonico, Barbara, et al.
Publicado: (2016)

The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders
por: Zhang, Sheng, et al.
Publicado: (2022)

Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells
por: Wang, Jing, et al.
Publicado: (2019)

Tollip Deficiency Alters Atherosclerosis and Steatosis by Disrupting Lipophagy
por: Chen, Keqiang, et al.
Publicado: (2017)

Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy
por: Han, Yachun, et al.
Publicado: (2021)

Impaired lipophagy in endothelial cells with prolonged exposure to oxidized low-density lipoprotein
por: Zhang, Cai-Ping, et al.
Publicado: (2020)

Novel cellular evidence of lipophagy within the Sertoli cells during spermatogenesis in the turtle
por: Ahmed, Nisar, et al.
Publicado: (2016)

The essential effect of mTORC1-dependent lipophagy in non-alcoholic fatty liver disease
por: Tan, Xiangyun, et al.
Publicado: (2023)

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast
por: Wang, Chao-Wen, et al.
Publicado: (2014)

Spatial distribution of lipid droplets during starvation: Implications for lipophagy
por: Barbosa, Antonio Daniel, et al.
Publicado: (2016)

Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases
por: Kloska, Anna, et al.
Publicado: (2020)

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes
por: Schott, Micah B., et al.
Publicado: (2019)

Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection
por: Wu, Keke, et al.
Publicado: (2021)

The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy
por: Zhang, Gaojian, et al.
Publicado: (2022)

Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells
por: Wang, Lin, et al.
Publicado: (2017)

Network pharmacology‐based dissection of the underlying mechanisms of dyspnoea induced by zedoary turmeric oil
por: Yang, Zhirui, et al.
Publicado: (2022)

Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment
por: Li, Qing, et al.
Publicado: (2023)

Synbiotics and Gut Microbiota: New Perspectives in the Treatment of Type 2 Diabetes Mellitus
por: Jiang, Haoran, et al.
Publicado: (2022)

AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae in Apis mellifera
por: Chen, Wen-Feng, et al.
Publicado: (2023)

UPR(ER) promotes lipophagy independent of chaperones to extend life span
por: Daniele, Joseph R., et al.
Publicado: (2020)

The Role of Lipophagy in the Development and Treatment of Non-Alcoholic Fatty Liver Disease
por: Grefhorst, Aldo, et al.
Publicado: (2021)

Nitrogen Starvation and Stationary Phase Lipophagy Have Distinct Molecular Mechanisms
por: Kumar, Ravinder, et al.
Publicado: (2020)

Feeding activates FGF15‐SHP‐TFEB‐mediated lipophagy in the gut
por: Seok, Sunmi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_as12poamkpe2mbln4svn13hggi