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Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1

The ER is a key organelle of membrane biogenesis and crucial for the folding of both membrane and secretory proteins. Sensors of the unfolded protein response (UPR) monitor the unfolded protein load in the ER and convey effector functions for maintaining ER homeostasis. Aberrant compositions of the...

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Detalles Bibliográficos
Autores principales:	Väth, Kristina, Mattes, Carsten, Reinhard, John, Covino, Roberto, Stumpf, Heike, Hummer, Gerhard, Ernst, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256922/ https://www.ncbi.nlm.nih.gov/pubmed/34196665 http://dx.doi.org/10.1083/jcb.202011078

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