Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo

γδ T cells form an integral arm of the immune system and are critical during protective and destructive immunity. However, how γδ T cells are functionally programmed in vivo remains unclear. Here, we employ RBPJ-inducible and KN6-transgenic mice to assess the roles of ontogenic timing, T cell recept...

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Detalles Bibliográficos
Autores principales: Chen, Edward L.Y., Lee, Christina R., Thompson, Patrycja K., Wiest, David L., Anderson, Michele K., Zúñiga-Pflücker, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256923/
https://www.ncbi.nlm.nih.gov/pubmed/34107257
http://dx.doi.org/10.1016/j.celrep.2021.109227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256923/
https://www.ncbi.nlm.nih.gov/pubmed/34107257
http://dx.doi.org/10.1016/j.celrep.2021.109227

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