MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages

MYC activates different metabolic programs in a cell-type- and cell-status-dependent manner. However, the role of MYC in inflammatory macrophages has not yet been determined. Metabolic and molecular analyses reveal that MYC, but not hypoxia inducible factor 1 (HIF1), is involved in enhancing early g...

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Detalles Bibliográficos
Autores principales: Bae, Seyeon, Uk Park, Peter Sang, Lee, Yeji, Mun, Se Hwan, Giannopoulou, Eugenia, Fujii, Takayuki, Lee, Kelvin P., Violante, Sara Nunes, Cross, Justin R., Park-Min, Kyung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257047/
https://www.ncbi.nlm.nih.gov/pubmed/34133930
http://dx.doi.org/10.1016/j.celrep.2021.109264

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