Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl(4)-Induced Liver Fibrosis

BACKGROUND: Liver fibrosis is a chronic liver disease with excessive production of extracellular matrix proteins, leading to cirrhosis, hepatocellular carcinoma, and death. PURPOSE: This study aimed at the development of a novel derivative of polyethyleneimine (PEI) that can effectively deliver tran...

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Detalles Bibliográficos
Autores principales: Ullah, Aftab, Chen, Gang, Hussain, Abid, Khan, Hanif, Abbas, Azar, Zhou, Zhanwei, Shafiq, Muhammad, Ahmad, Saleem, Ali, Usman, Usman, Muhammad, Raza, Faisal, Ahmed, Abrar, Qiu, Zijie, Zheng, Maochao, Liu, Daojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257077/
https://www.ncbi.nlm.nih.gov/pubmed/34234436
http://dx.doi.org/10.2147/IJN.S314367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257077/
https://www.ncbi.nlm.nih.gov/pubmed/34234436
http://dx.doi.org/10.2147/IJN.S314367

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