Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity

Mortality from breast cancer is almost exclusively a result of tumor metastasis, and lungs are one of the main metastatic sites. Cancer-associated fibroblasts are prominent players in the microenvironment of breast cancer. However, their role in the metastatic niche is largely unknown. In this study...

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Detalles Bibliográficos
Autores principales: Shani, Ophir, Raz, Yael, Monteran, Lea, Scharff, Ye'ela, Levi-Galibov, Oshrat, Megides, Or, Shacham, Hila, Cohen, Noam, Silverbush, Dana, Avivi, Camilla, Sharan, Roded, Madi, Asaf, Scherz-Shouval, Ruth, Barshack, Iris, Tsarfaty, Ilan, Erez, Neta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257251/
https://www.ncbi.nlm.nih.gov/pubmed/34169837
http://dx.doi.org/10.7554/eLife.60745

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