Efficient TALEN-mediated gene knockin at the bovine Y chromosome and generation of a sex-reversal bovine

Functional elucidation of bovine Y-chromosome genes requires available genome editing technologies. Meanwhile, it has yet to be proven whether the bovine Sry gene is the main or single factor involved in the development of the male phenotype in bovine. Here, we efficiently knocked out four Y-linked...

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Detalles Bibliográficos
Autores principales: Wang, Ming, Sun, ZhaoLin, Ding, Fangrong, Wang, Haiping, Li, Ling, Li, Xue, Zheng, Xianjin, Li, Ning, Dai, Yunping, Wu, Changxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257526/
https://www.ncbi.nlm.nih.gov/pubmed/34047803
http://dx.doi.org/10.1007/s00018-021-03855-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257526/
https://www.ncbi.nlm.nih.gov/pubmed/34047803
http://dx.doi.org/10.1007/s00018-021-03855-1

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