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Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance

Parkinson’s disease (PD) is a neurodegenerative, progressive disease without a cure. To prevent PD onset or at least limit neurodegeneration, a better understanding of the underlying cellular and molecular disease mechanisms is crucial. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene repr...

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Detalles Bibliográficos
Autores principales:	Streubel-Gallasch, Linn, Giusti, Veronica, Sandre, Michele, Tessari, Isabella, Plotegher, Nicoletta, Giusto, Elena, Masato, Anna, Iovino, Ludovica, Battisti, Ilaria, Arrigoni, Giorgio, Shimshek, Derya, Greggio, Elisa, Tremblay, Marie-Eve, Bubacco, Luigi, Erlandsson, Anna, Civiero, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257537/ https://www.ncbi.nlm.nih.gov/pubmed/33629273 http://dx.doi.org/10.1007/s12035-021-02327-8

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