Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner

Muscular dystrophies are debilitating neuromuscular disorders for which no cure exists. As this disorder affects both cardiac and skeletal muscle, patients would benefit from a cellular therapy that can simultaneously regenerate both tissues. The current protocol to derive bipotent mesodermal progen...

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Detalles Bibliográficos
Autores principales: Breuls, Natacha, Giarratana, Nefele, Yedigaryan, Laura, Garrido, Gabriel Miró, Carai, Paolo, Heymans, Stephane, Ranga, Adrian, Deroose, Christophe, Sampaolesi, Maurilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257578/
https://www.ncbi.nlm.nih.gov/pubmed/34226515
http://dx.doi.org/10.1038/s41419-021-03936-w

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