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Association of body mass index and maternal age with first stage duration of labour

To evaluate associations between early-pregnancy body mass index (BMI) and active first stage labour duration, accounting for possible interaction with maternal age, we conducted a cohort study of women with spontaneous onset of labour allocated to Robson group 1. Quantile regression analysis was pe...

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Autores principales: Lundborg, Louise, Liu, Xingrong, Åberg, Katarina, Sandström, Anna, Tilden, Ellen L., Stephansson, Olof, Ahlberg, Mia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257589/
https://www.ncbi.nlm.nih.gov/pubmed/34226624
http://dx.doi.org/10.1038/s41598-021-93217-5
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author Lundborg, Louise
Liu, Xingrong
Åberg, Katarina
Sandström, Anna
Tilden, Ellen L.
Stephansson, Olof
Ahlberg, Mia
author_facet Lundborg, Louise
Liu, Xingrong
Åberg, Katarina
Sandström, Anna
Tilden, Ellen L.
Stephansson, Olof
Ahlberg, Mia
author_sort Lundborg, Louise
collection PubMed
description To evaluate associations between early-pregnancy body mass index (BMI) and active first stage labour duration, accounting for possible interaction with maternal age, we conducted a cohort study of women with spontaneous onset of labour allocated to Robson group 1. Quantile regression analysis was performed to estimate first stage labour duration between BMI categories in two maternal age subgroups (more and less than 30 years). Results show that obesity (BMI > 30) among younger women (< 30 years) increased the median labour duration of first stage by 30 min compared with normal weight women (BMI < 25), and time difference estimated at the 90th quantile was more than 1 h. Active first stage labour time differences between obese and normal weight women was modified by maternal age. In conclusion: (a) obesity is associated with longer duration of first stage of labour, and (b) maternal age is an effect modifier for this association. This novel finding of an effect modification between BMI and maternal age contributes to the body of evidence that supports a more individualized approach when describing labour duration.
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spelling pubmed-82575892021-07-06 Association of body mass index and maternal age with first stage duration of labour Lundborg, Louise Liu, Xingrong Åberg, Katarina Sandström, Anna Tilden, Ellen L. Stephansson, Olof Ahlberg, Mia Sci Rep Article To evaluate associations between early-pregnancy body mass index (BMI) and active first stage labour duration, accounting for possible interaction with maternal age, we conducted a cohort study of women with spontaneous onset of labour allocated to Robson group 1. Quantile regression analysis was performed to estimate first stage labour duration between BMI categories in two maternal age subgroups (more and less than 30 years). Results show that obesity (BMI > 30) among younger women (< 30 years) increased the median labour duration of first stage by 30 min compared with normal weight women (BMI < 25), and time difference estimated at the 90th quantile was more than 1 h. Active first stage labour time differences between obese and normal weight women was modified by maternal age. In conclusion: (a) obesity is associated with longer duration of first stage of labour, and (b) maternal age is an effect modifier for this association. This novel finding of an effect modification between BMI and maternal age contributes to the body of evidence that supports a more individualized approach when describing labour duration. Nature Publishing Group UK 2021-07-05 /pmc/articles/PMC8257589/ /pubmed/34226624 http://dx.doi.org/10.1038/s41598-021-93217-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lundborg, Louise
Liu, Xingrong
Åberg, Katarina
Sandström, Anna
Tilden, Ellen L.
Stephansson, Olof
Ahlberg, Mia
Association of body mass index and maternal age with first stage duration of labour
title Association of body mass index and maternal age with first stage duration of labour
title_full Association of body mass index and maternal age with first stage duration of labour
title_fullStr Association of body mass index and maternal age with first stage duration of labour
title_full_unstemmed Association of body mass index and maternal age with first stage duration of labour
title_short Association of body mass index and maternal age with first stage duration of labour
title_sort association of body mass index and maternal age with first stage duration of labour
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257589/
https://www.ncbi.nlm.nih.gov/pubmed/34226624
http://dx.doi.org/10.1038/s41598-021-93217-5
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