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Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade

Hedgehog signaling plays a pivotal role in embryonic pattern formation and diverse aspects of the postnatal biological process. Perturbation of the hedgehog pathway and overexpression of GLI1, a downstream transcription factor in the hedgehog pathway, are highly relevant to several malignancies incl...

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Detalles Bibliográficos
Autores principales:	Wang, Wei, Yan, Taiqiang, Guo, Wei, Niu, Jianfang, Zhao, Zhiqing, Sun, Kunkun, Zhang, Hongliang, Yu, Yiyang, Ren, Tingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257592/ https://www.ncbi.nlm.nih.gov/pubmed/33637972 http://dx.doi.org/10.1038/s41418-021-00749-4

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