Cargando…
Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
Effective treatments of neurodegenerative diseases require drugs to be actively transported across the blood-brain barrier (BBB). However, nanoparticle drug carriers explored for this purpose show negligible brain uptake, and the lack of basic understanding of nanoparticle-BBB interactions underlies...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257611/ https://www.ncbi.nlm.nih.gov/pubmed/34226541 http://dx.doi.org/10.1038/s41467-021-24323-1 |