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A miRNA signature predicts benefit from addition of hypoxia-modifying therapy to radiation treatment in invasive bladder cancer

BACKGROUND: miRNAs are promising biomarkers in oncology as their small size makes them less susceptible to degradation than mRNA in FFPE tissue. We aimed to derive a hypoxia-associated miRNA signature for bladder cancer. METHODS: Taqman miRNA array cards identified miRNA seed genes induced under hyp...

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Detalles Bibliográficos
Autores principales: Khan, Mairah T., Irlam-Jones, Joely J., Pereira, Ronnie Rodrigues, Lane, Brian, Valentine, Helen R., Aragaki, Kai, Dyrskjøt, Lars, McConkey, David J., Hoskin, Peter J., Choudhury, Ananya, West, Catharine M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257670/
https://www.ncbi.nlm.nih.gov/pubmed/33846523
http://dx.doi.org/10.1038/s41416-021-01326-9

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