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OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation
In bacterial and sterile inflammation of the liver, hepatocyte apoptosis is, in contrast to necroptosis, a common feature. The molecular mechanisms preventing hepatocyte necroptosis and the potential consequences of hepatocyte necroptosis are largely unknown. Apoptosis and necroptosis are critically...
Autores principales: | Koschel, Josephin, Nishanth, Gopala, Just, Sissy, Harit, Kunjan, Kröger, Andrea, Deckert, Martina, Naumann, Michael, Schlüter, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257688/ https://www.ncbi.nlm.nih.gov/pubmed/33712742 http://dx.doi.org/10.1038/s41418-021-00752-9 |
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