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Operative ubiquitin-specific protease 22 deubiquitination confers a more invasive phenotype to cholangiocarcinoma

Oncogenic ubiquitin-specific protease 22 (USP22) is implicated in a variety of tumours; however, evidence of its role and underlying molecular mechanisms in cholangiocarcinoma (CCA) development remains unknown. We collected paired tumour and adjacent non-tumour tissues from 57 intrahepatic CCA (iCCA...

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Detalles Bibliográficos
Autores principales: Tian, Yu, Tang, Bo, Wang, Chengye, Wang, Yan, Mao, Jiakai, Yao, Yifan, Gao, Zhenming, Liang, Rui, Ye, Mingliang, Cai, Shijie, Wang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257691/
https://www.ncbi.nlm.nih.gov/pubmed/34226501
http://dx.doi.org/10.1038/s41419-021-03940-0