Evidence that polyploidy in esophageal adenocarcinoma originates from mitotic slippage caused by defective chromosome attachments

Polyploidy is present in many cancer types and is increasingly recognized as an important factor in promoting chromosomal instability, genome evolution, and heterogeneity in cancer cells. However, the mechanisms that trigger polyploidy in cancer cells are largely unknown. In this study, we investiga...

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Detalles Bibliográficos
Autores principales: Scott, Stacey J., Li, Xiaodun, Jammula, Sriganesh, Devonshire, Ginny, Lindon, Catherine, Fitzgerald, Rebecca C., D’Avino, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257792/
https://www.ncbi.nlm.nih.gov/pubmed/33649470
http://dx.doi.org/10.1038/s41418-021-00745-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257792/
https://www.ncbi.nlm.nih.gov/pubmed/33649470
http://dx.doi.org/10.1038/s41418-021-00745-8

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