Cargando…
Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma
To assess the maximal lymph nodal diameter on the 8th edition American Joint Committee on Cancer staging system of nasopharyngeal carcinoma (NPC). This study extracted NPC patients between 2004 and 2016 in the Surveillance, Epidemiology, and End Results database. Included patients were divided into...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257890/ https://www.ncbi.nlm.nih.gov/pubmed/34190192 http://dx.doi.org/10.1097/MD.0000000000026543 |
_version_ | 1783718398495031296 |
---|---|
author | Huang, Shi-Ting Qu, Song Li, Ling Chen, Kai-Hua Zhu, Xiao-Dong Pan, Xin-Bin |
author_facet | Huang, Shi-Ting Qu, Song Li, Ling Chen, Kai-Hua Zhu, Xiao-Dong Pan, Xin-Bin |
author_sort | Huang, Shi-Ting |
collection | PubMed |
description | To assess the maximal lymph nodal diameter on the 8th edition American Joint Committee on Cancer staging system of nasopharyngeal carcinoma (NPC). This study extracted NPC patients between 2004 and 2016 in the Surveillance, Epidemiology, and End Results database. Included patients were divided into 3 groups: ≤3 cm, >3–6 cm, and >6 cm based on the maximal lymph nodal diameter. Cumulative survival curves of 5-year overall survival (OS) and cancer-specific survival (CSS) were calculated using the Kaplan-Meier method between the 3 groups. The 5-year OS (64.0% vs 59.3%, P = .240) and CSS (71.8% vs 67.0%, P = .242) of ≤3 cm and >3–6 cm groups were not different. In contrast, the 5-year OS and CSS were different between >6 cm and ≤3 cm groups, and between >6 cm and >3–6 cm groups. The stratified hazard ratio of OS and CSS was 1.75 (95% confidence interval: 1.25–2.45; P = .001) and 1.77 (95% confidence interval: 1.20–2.60; P = .004) for the >6 cm group in the multivariate regression analysis. It is reasonable that the maximal lymph nodal diameter with >6 cm is classified as stage N3 of the 8th edition American Joint Committee on Cancer staging system for NPC. |
format | Online Article Text |
id | pubmed-8257890 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-82578902021-07-08 Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma Huang, Shi-Ting Qu, Song Li, Ling Chen, Kai-Hua Zhu, Xiao-Dong Pan, Xin-Bin Medicine (Baltimore) 5700 To assess the maximal lymph nodal diameter on the 8th edition American Joint Committee on Cancer staging system of nasopharyngeal carcinoma (NPC). This study extracted NPC patients between 2004 and 2016 in the Surveillance, Epidemiology, and End Results database. Included patients were divided into 3 groups: ≤3 cm, >3–6 cm, and >6 cm based on the maximal lymph nodal diameter. Cumulative survival curves of 5-year overall survival (OS) and cancer-specific survival (CSS) were calculated using the Kaplan-Meier method between the 3 groups. The 5-year OS (64.0% vs 59.3%, P = .240) and CSS (71.8% vs 67.0%, P = .242) of ≤3 cm and >3–6 cm groups were not different. In contrast, the 5-year OS and CSS were different between >6 cm and ≤3 cm groups, and between >6 cm and >3–6 cm groups. The stratified hazard ratio of OS and CSS was 1.75 (95% confidence interval: 1.25–2.45; P = .001) and 1.77 (95% confidence interval: 1.20–2.60; P = .004) for the >6 cm group in the multivariate regression analysis. It is reasonable that the maximal lymph nodal diameter with >6 cm is classified as stage N3 of the 8th edition American Joint Committee on Cancer staging system for NPC. Lippincott Williams & Wilkins 2021-07-02 /pmc/articles/PMC8257890/ /pubmed/34190192 http://dx.doi.org/10.1097/MD.0000000000026543 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 5700 Huang, Shi-Ting Qu, Song Li, Ling Chen, Kai-Hua Zhu, Xiao-Dong Pan, Xin-Bin Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma |
title | Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma |
title_full | Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma |
title_fullStr | Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma |
title_full_unstemmed | Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma |
title_short | Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma |
title_sort | maximal lymph nodal diameter on n stage of nasopharyngeal carcinoma |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257890/ https://www.ncbi.nlm.nih.gov/pubmed/34190192 http://dx.doi.org/10.1097/MD.0000000000026543 |
work_keys_str_mv | AT huangshiting maximallymphnodaldiameteronnstageofnasopharyngealcarcinoma AT qusong maximallymphnodaldiameteronnstageofnasopharyngealcarcinoma AT liling maximallymphnodaldiameteronnstageofnasopharyngealcarcinoma AT chenkaihua maximallymphnodaldiameteronnstageofnasopharyngealcarcinoma AT zhuxiaodong maximallymphnodaldiameteronnstageofnasopharyngealcarcinoma AT panxinbin maximallymphnodaldiameteronnstageofnasopharyngealcarcinoma |