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Mifepristone (RU486) inhibits dietary lipid digestion by antagonizing the role of glucocorticoid receptor on lipase transcription

Lipid digestion and absorption are tightly regulated to cope with metabolic demands among tissues. How these processes are coordinated is not well characterized. Here, we found that mifepristone (RU486) prevents lipid digestion both in flies and mice. In flies, RU486 administration suppresses lipid...

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Detalles Bibliográficos
Autores principales:	Ma, Peng, Zhang, Yao, Liang, Qiying, Yin, Youjie, Wang, Saifei, Han, Ruolei, Huo, Chunyu, Deng, Hansong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257970/ https://www.ncbi.nlm.nih.gov/pubmed/34308280 http://dx.doi.org/10.1016/j.isci.2021.102507

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