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Efficient pre-treatment for pancreatic cancer using chloroquine-loaded nanoparticles targeting pancreatic stellate cells
Pancreatic stellate cells (PSCs) play a key role in desmoplastic stroma, which is a characteristic of pancreatic ductal adenocarcinoma (PDAC), and they also enhance the malignancy of pancreatic cancer cells. Our previous study reported chloroquine's mitigating effects on PSC activation; however...
Autores principales: | Matsumoto, Sokichi, Nakata, Kohei, Sagara, Akiko, Guan, Weiyu, Ikenaga, Naoki, Ohuchida, Kenoki, Nakamura, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258615/ https://www.ncbi.nlm.nih.gov/pubmed/34267825 http://dx.doi.org/10.3892/ol.2021.12894 |
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