Cargando…

A computational multi-targeting approach for drug repositioning for psoriasis treatment

BACKGROUND: Psoriasis is an autoimmune inflammatory skin disease that affects 0.5–3% of the world’s population and current treatment options are posed with limitations. The reduced risk of failure in clinical trials for repositioned drug candidates and the time and cost-effectiveness has popularized...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ibezim, Akachukwu, Onah, Emmanuel, Dim, Ebubechukwu N., Ntie-Kang, Fidele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258956/ https://www.ncbi.nlm.nih.gov/pubmed/34225727 http://dx.doi.org/10.1186/s12906-021-03359-2

Ejemplares similares

Anti-Trypanosomal Activity of Nigerian Plants and Their Constituents
por: Nwodo, Ngozi Justina, et al.
Publicado: (2015)

Fragment-based virtual screening discovers potential new Plasmodium PI4KIIIβ ligands
por: Ibezim, Akachukwu, et al.
Publicado: (2022)

The Immunogenetics of Psoriasis and Implications for Drug Repositioning
por: Xu, Xuan, et al.
Publicado: (2017)

Prediction of HIV-1 protease cleavage site from octapeptide sequence information using selected classifiers and hybrid descriptors
por: Onah, Emmanuel, et al.
Publicado: (2022)

System and network biology-based computational approaches for drug repositioning
por: Pandita, Vasundhara, et al.
Publicado: (2022)

An in silico evaluation of the ADMET profile of the StreptomeDB database
por: Ntie-Kang, Fidele
Publicado: (2013)

Structure-based virtual screening and molecular dynamics simulation studies to discover new SARS-CoV-2 main protease inhibitors
por: Ibezim, A., et al.
Publicado: (2021)

Drug repositioning prediction for psoriasis using the adverse event reporting database
por: Ko, Minoh, et al.
Publicado: (2023)

Changing Trends in Computational Drug Repositioning
por: Yella, Jaswanth K., et al.
Publicado: (2018)

A network integration approach for drug-target interaction prediction and computational drug repositioning from heterogeneous information
por: Luo, Yunan, et al.
Publicado: (2017)

Experimental and In-Silico Investigation of Anti-Microbial Activity of 1-Chloro-2-Isocyanatoethane Derivatives of Thiomorpholine, Piperazine and Morpholine
por: Nwuche, Charles O., et al.
Publicado: (2017)

Synthesis, molecular docking, antiplasmodial and antioxidant activities of new sulfonamido-pepetide derivatives
por: Onoabedje, Efeturi A., et al.
Publicado: (2020)

New sulphonamide pyrolidine carboxamide derivatives: Synthesis, molecular docking, antiplasmodial and antioxidant activities
por: Onoabedje, Efeturi A., et al.
Publicado: (2021)

Repositioning Drugs for Rare Diseases Based on Biological Features and Computational Approaches
por: Otero-Carrasco, Belén, et al.
Publicado: (2022)

Multi-target drug repositioning by bipartite block-wise sparse multi-task learning
por: Li, Limin, et al.
Publicado: (2018)

Natural Products as Potential Lead Compounds for Drug Discovery Against SARS-CoV-2
por: Ebob, Oyere Tanyi, et al.
Publicado: (2021)

Drug repositioning or target repositioning: A structural perspective of drug-target-indication relationship for available repurposed drugs
por: Parisi, Daniele, et al.
Publicado: (2020)

Computational Discovery of Putative Leads for Drug Repositioning through Drug-Target Interaction Prediction
por: Coelho, Edgar D., et al.
Publicado: (2016)

Review of Drug Repositioning Approaches and Resources
por: Xue, Hanqing, et al.
Publicado: (2018)

Computational drug repositioning of atorvastatin for ulcerative colitis
por: Bai, Lawrence, et al.
Publicado: (2021)

Editorial to Special Issue—“Structure-Activity Relationships (SAR) of Natural Products”
por: Sippl, Wolfgang, et al.
Publicado: (2021)

A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions
por: Jarada, Tamer N., et al.
Publicado: (2020)

Drug repositioning: computational approaches and research examples classified according to the evidence level
por: Vogrinc, David, et al.
Publicado: (2017)

Drug Target Prediction and Repositioning Using an Integrated Network-Based Approach
por: Emig, Dorothea, et al.
Publicado: (2013)

Large-scale computational drug repositioning to find treatments for rare diseases
por: Govindaraj, Rajiv Gandhi, et al.
Publicado: (2018)

Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer
por: Rabben, Hanne-Line, et al.
Publicado: (2021)

Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment
por: Nagaraj, A B, et al.
Publicado: (2018)

Systematic Approach for Drug Repositioning of Anti-Epileptic Drugs
por: Ko, Younhee, et al.
Publicado: (2019)

Molecular interaction networks and drug development: Novel approach to drug target identification and drug repositioning
por: Loscalzo, Joseph
Publicado: (2022)

From drug repositioning to target repositioning: prediction of therapeutic targets using genetically perturbed transcriptomic signatures
por: Namba, Satoko, et al.
Publicado: (2022)

Computational drug repositioning through heterogeneous network clustering
por: Wu, Chao, et al.
Publicado: (2013)

A review of validation strategies for computational drug repositioning
por: Brown, Adam S, et al.
Publicado: (2016)

Hybrid attentional memory network for computational drug repositioning
por: He, Jieyue, et al.
Publicado: (2020)

Repositioning of the antipsychotic drug TFP for sepsis treatment
por: Park, Jung Hwa, et al.
Publicado: (2019)

Computational approaches for drug repositioning and repurposing to combat SARS-CoV-2 infection
por: Panda, Subhamay, et al.
Publicado: (2022)

Repositioning of Antiparasitic Drugs for Tumor Treatment
por: Li, Yan-Qi, et al.
Publicado: (2021)

Drug Screening and Drug Repositioning as Promising Therapeutic Approaches for Spinal Muscular Atrophy Treatment
por: Menduti, Giovanna, et al.
Publicado: (2020)

Drug repositioning targeting glutaminase reveals drug candidates for the treatment of Alzheimer’s disease patients
por: Bayraktar, Abdulahad, et al.
Publicado: (2023)

Oxazin-5-Ones as a Novel Class of Penicillin Binding Protein Inhibitors: Design, Synthesis and Structure Activity Relationship
por: Onoabedje, Efeturi Abraham, et al.
Publicado: (2016)

ksRepo: a generalized platform for computational drug repositioning
por: Brown, Adam S., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_eetb8s2djf7ueuai86sigic8fk