Integrated in silico MS-based phosphoproteomics and network enrichment analysis of RASopathy proteins

BACKGROUND: RASopathies are a group of syndromes showing clinical overlap caused by mutations in genes affecting the RAS-MAPK pathway. Consequent disruption on cellular signaling leads and is driven by phosphoproteome remodeling. However, we still lack a comprehensive picture of the different key pl...

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Detalles Bibliográficos
Autores principales: Montero-Bullón, Javier-Fernando, González-Velasco, Óscar, Isidoro-García, María, Lacal, Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258961/
https://www.ncbi.nlm.nih.gov/pubmed/34229750
http://dx.doi.org/10.1186/s13023-021-01934-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258961/
https://www.ncbi.nlm.nih.gov/pubmed/34229750
http://dx.doi.org/10.1186/s13023-021-01934-x

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